Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia
Апстракт
The growing clinical interest and use of soybean-based food products and extracts to increase dietary phytoestrogen intake have led to medical interest in the precise determination of the phytoestrogen composition of soybean products. We have analyzed the composition of these compounds in 20 domestic and introduced varieties of genetically non-modified soybean genotypes grown under the same agroecological conditions. The isoflavone content of soybeans cultivated in this region of Serbia has not been previously reported. The assays were performed, after extraction with methanol-water (8:2, v/v), by C-18 reversed phase high-performance liquid chromatography coupled with photodiode array detection. The total phytoestrogen concentration was found to be between 2.24 and 3.79 mg g(-1) dry bean weight. The total concentration of daidzein and its derivatives ranged from 0.96 to 1.82 mg g(-1), total glyciteines from 0.34-0.53 mg g(-1), and all genistein derivatives from 0.86-1.67 mg g(-1) dry b...ean weight. Given the high biological potency of phytoestrogens and their metabolic conversion products, our data suggest that phytoestrogen content screening could be a useful tool in the selection of soybean genotypes with improved health promoting characteristics.
Кључне речи:
phytoestrogens / soybean / HPLC analysisИзвор:
Natural Product Communications, 2009, 4, 8, 1069-1074Издавач:
- Natural Product Incorporation
Финансирање / пројекти:
- Ministry of Science and Technological Development, Republic of Serbia
DOI: 10.1177/1934578x0900400810
ISSN: 1934-578X
PubMed: 19768985
WoS: 000269433300010
Scopus: 2-s2.0-73949101377
Колекције
Институција/група
FiVeRTY - JOUR AU - Cvejić, Jelena AU - Malenčić, Ðorđe AU - Tepavčević, Vesna AU - Posa, Mihalj AU - Miladinović, Jegor PY - 2009 UR - http://fiver.ifvcns.rs/handle/123456789/772 AB - The growing clinical interest and use of soybean-based food products and extracts to increase dietary phytoestrogen intake have led to medical interest in the precise determination of the phytoestrogen composition of soybean products. We have analyzed the composition of these compounds in 20 domestic and introduced varieties of genetically non-modified soybean genotypes grown under the same agroecological conditions. The isoflavone content of soybeans cultivated in this region of Serbia has not been previously reported. The assays were performed, after extraction with methanol-water (8:2, v/v), by C-18 reversed phase high-performance liquid chromatography coupled with photodiode array detection. The total phytoestrogen concentration was found to be between 2.24 and 3.79 mg g(-1) dry bean weight. The total concentration of daidzein and its derivatives ranged from 0.96 to 1.82 mg g(-1), total glyciteines from 0.34-0.53 mg g(-1), and all genistein derivatives from 0.86-1.67 mg g(-1) dry bean weight. Given the high biological potency of phytoestrogens and their metabolic conversion products, our data suggest that phytoestrogen content screening could be a useful tool in the selection of soybean genotypes with improved health promoting characteristics. PB - Natural Product Incorporation T2 - Natural Product Communications T1 - Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia EP - 1074 IS - 8 SP - 1069 VL - 4 DO - 10.1177/1934578x0900400810 ER -
@article{ author = "Cvejić, Jelena and Malenčić, Ðorđe and Tepavčević, Vesna and Posa, Mihalj and Miladinović, Jegor", year = "2009", abstract = "The growing clinical interest and use of soybean-based food products and extracts to increase dietary phytoestrogen intake have led to medical interest in the precise determination of the phytoestrogen composition of soybean products. We have analyzed the composition of these compounds in 20 domestic and introduced varieties of genetically non-modified soybean genotypes grown under the same agroecological conditions. The isoflavone content of soybeans cultivated in this region of Serbia has not been previously reported. The assays were performed, after extraction with methanol-water (8:2, v/v), by C-18 reversed phase high-performance liquid chromatography coupled with photodiode array detection. The total phytoestrogen concentration was found to be between 2.24 and 3.79 mg g(-1) dry bean weight. The total concentration of daidzein and its derivatives ranged from 0.96 to 1.82 mg g(-1), total glyciteines from 0.34-0.53 mg g(-1), and all genistein derivatives from 0.86-1.67 mg g(-1) dry bean weight. Given the high biological potency of phytoestrogens and their metabolic conversion products, our data suggest that phytoestrogen content screening could be a useful tool in the selection of soybean genotypes with improved health promoting characteristics.", publisher = "Natural Product Incorporation", journal = "Natural Product Communications", title = "Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia", pages = "1074-1069", number = "8", volume = "4", doi = "10.1177/1934578x0900400810" }
Cvejić, J., Malenčić, Ð., Tepavčević, V., Posa, M.,& Miladinović, J.. (2009). Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia. in Natural Product Communications Natural Product Incorporation., 4(8), 1069-1074. https://doi.org/10.1177/1934578x0900400810
Cvejić J, Malenčić Ð, Tepavčević V, Posa M, Miladinović J. Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia. in Natural Product Communications. 2009;4(8):1069-1074. doi:10.1177/1934578x0900400810 .
Cvejić, Jelena, Malenčić, Ðorđe, Tepavčević, Vesna, Posa, Mihalj, Miladinović, Jegor, "Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia" in Natural Product Communications, 4, no. 8 (2009):1069-1074, https://doi.org/10.1177/1934578x0900400810 . .