Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species
No Thumbnail
Authors
Radovanović, KatarinaGavarić, Neda
Švarc-Gajić, Jaroslava

Brezo-Borjan, Tanja
Zlatković, Bojan
Lončar, Biljana
Aćimović, Milica

Article (Published version)
Metadata
Show full item recordAbstract
The genus Achillea has significant medical potential due to the presence of highly bioactive compounds in its chemical composition. To take advantage of plants’ biomedical potential, it is of great importance to use a proper extraction process. This study aimed to determine and compare the preliminary chemical composition of five different Achillea species extracted with two conventional (infusion and maceration) and two non-conventional (ultrasound-assisted extraction (UAE) and Subcritical water extraction (SWE)) techniques. The extracts were prepared using the previously described procedures for infusion, maceration, UAE and SWE extraction. For all extracts, the extraction yield (dry extract (DE)) was determined. The analyzed extracts were preliminarily chemically characterized spectrophotometrically in terms of total phenolic content (TPC) and total flavonoid content (TFC). The obtained results showed that non-conventional techniques delivered higher values of TPC and TFC than conve...ntional. There is a statistically significant increase in DE and TPC content when applying SWE for all observed Achillea species. The highest DE value, 48.80 ± 1.76%, was observed for A. asplenifolia. The highest TPC values were observed after applying SWE: 93.63 ± 1.01 mg GAE/g DE for A. millefolium, and 90.12 ± 0.87 mg GAE/g DE for A. crithmifolia. The results for TFC revealed a statistically significant difference in values, with A. nobilis subsp. nelreichii as the sample with the highest content of TFC (11.11 ± 0.22 mg QE/g DE) when using UAE. Consequently, it could be concluded that SWE is a superior non-conventional extraction technique, and A. nobilis subsp. nerleichii presents as the most promising plant.
Keywords:
yarrow / green extraction techniques / phenolic compounds / principal component analysis / PCA / AchilleaSource:
Processes - Basel, 2023, 11, 1, 86-Publisher:
- Basel : MDPI
Funding / projects:
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200032 (Institute of Field and Vegetable Crops, Novi Sad) (RS-200032)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200134 (University of Novi Sad, Faculty of Technology) (RS-200134)
- Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200114 (University of Novi Sad, Faculty of Medicine) (RS-200114)
Collections
Institution/Community
FiVeRTY - JOUR AU - Radovanović, Katarina AU - Gavarić, Neda AU - Švarc-Gajić, Jaroslava AU - Brezo-Borjan, Tanja AU - Zlatković, Bojan AU - Lončar, Biljana AU - Aćimović, Milica PY - 2023 UR - http://fiver.ifvcns.rs/handle/123456789/3342 AB - The genus Achillea has significant medical potential due to the presence of highly bioactive compounds in its chemical composition. To take advantage of plants’ biomedical potential, it is of great importance to use a proper extraction process. This study aimed to determine and compare the preliminary chemical composition of five different Achillea species extracted with two conventional (infusion and maceration) and two non-conventional (ultrasound-assisted extraction (UAE) and Subcritical water extraction (SWE)) techniques. The extracts were prepared using the previously described procedures for infusion, maceration, UAE and SWE extraction. For all extracts, the extraction yield (dry extract (DE)) was determined. The analyzed extracts were preliminarily chemically characterized spectrophotometrically in terms of total phenolic content (TPC) and total flavonoid content (TFC). The obtained results showed that non-conventional techniques delivered higher values of TPC and TFC than conventional. There is a statistically significant increase in DE and TPC content when applying SWE for all observed Achillea species. The highest DE value, 48.80 ± 1.76%, was observed for A. asplenifolia. The highest TPC values were observed after applying SWE: 93.63 ± 1.01 mg GAE/g DE for A. millefolium, and 90.12 ± 0.87 mg GAE/g DE for A. crithmifolia. The results for TFC revealed a statistically significant difference in values, with A. nobilis subsp. nelreichii as the sample with the highest content of TFC (11.11 ± 0.22 mg QE/g DE) when using UAE. Consequently, it could be concluded that SWE is a superior non-conventional extraction technique, and A. nobilis subsp. nerleichii presents as the most promising plant. PB - Basel : MDPI T2 - Processes - Basel T1 - Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species IS - 1 SP - 86 VL - 11 DO - 10.3390/pr11010086 ER -
@article{ author = "Radovanović, Katarina and Gavarić, Neda and Švarc-Gajić, Jaroslava and Brezo-Borjan, Tanja and Zlatković, Bojan and Lončar, Biljana and Aćimović, Milica", year = "2023", abstract = "The genus Achillea has significant medical potential due to the presence of highly bioactive compounds in its chemical composition. To take advantage of plants’ biomedical potential, it is of great importance to use a proper extraction process. This study aimed to determine and compare the preliminary chemical composition of five different Achillea species extracted with two conventional (infusion and maceration) and two non-conventional (ultrasound-assisted extraction (UAE) and Subcritical water extraction (SWE)) techniques. The extracts were prepared using the previously described procedures for infusion, maceration, UAE and SWE extraction. For all extracts, the extraction yield (dry extract (DE)) was determined. The analyzed extracts were preliminarily chemically characterized spectrophotometrically in terms of total phenolic content (TPC) and total flavonoid content (TFC). The obtained results showed that non-conventional techniques delivered higher values of TPC and TFC than conventional. There is a statistically significant increase in DE and TPC content when applying SWE for all observed Achillea species. The highest DE value, 48.80 ± 1.76%, was observed for A. asplenifolia. The highest TPC values were observed after applying SWE: 93.63 ± 1.01 mg GAE/g DE for A. millefolium, and 90.12 ± 0.87 mg GAE/g DE for A. crithmifolia. The results for TFC revealed a statistically significant difference in values, with A. nobilis subsp. nelreichii as the sample with the highest content of TFC (11.11 ± 0.22 mg QE/g DE) when using UAE. Consequently, it could be concluded that SWE is a superior non-conventional extraction technique, and A. nobilis subsp. nerleichii presents as the most promising plant.", publisher = "Basel : MDPI", journal = "Processes - Basel", title = "Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species", number = "1", pages = "86", volume = "11", doi = "10.3390/pr11010086" }
Radovanović, K., Gavarić, N., Švarc-Gajić, J., Brezo-Borjan, T., Zlatković, B., Lončar, B.,& Aćimović, M.. (2023). Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species. in Processes - Basel Basel : MDPI., 11(1), 86. https://doi.org/10.3390/pr11010086
Radovanović K, Gavarić N, Švarc-Gajić J, Brezo-Borjan T, Zlatković B, Lončar B, Aćimović M. Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species. in Processes - Basel. 2023;11(1):86. doi:10.3390/pr11010086 .
Radovanović, Katarina, Gavarić, Neda, Švarc-Gajić, Jaroslava, Brezo-Borjan, Tanja, Zlatković, Bojan, Lončar, Biljana, Aćimović, Milica, "Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species" in Processes - Basel, 11, no. 1 (2023):86, https://doi.org/10.3390/pr11010086 . .