The genus Achillea has significant medical potential due to the presence of highly bioactive compounds in its chemical composition. To take advantage of plants’ biomedical potential, it is of great importance to use a proper extraction process. This study aimed to determine and compare the preliminary chemical composition of five different Achillea species extracted with two conventional (infusion and maceration) and two non-conventional (ultrasound-assisted extraction (UAE) and Subcritical water extraction (SWE)) techniques. The extracts were prepared using the previously described procedures for infusion, maceration, UAE and SWE extraction. For all extracts, the extraction yield (dry extract (DE)) was determined. The analyzed extracts were preliminarily chemically characterized spectrophotometrically in terms of total phenolic content (TPC) and total flavonoid content (TFC). The obtained results showed that non-conventional techniques delivered higher values of TPC and TFC than conve...ntional. There is a statistically significant increase in DE and TPC content when applying SWE for all observed Achillea species. The highest DE value, 48.80 ± 1.76%, was observed for A. asplenifolia. The highest TPC values were observed after applying SWE: 93.63 ± 1.01 mg GAE/g DE for A. millefolium, and 90.12 ± 0.87 mg GAE/g DE for A. crithmifolia. The results for TFC revealed a statistically significant difference in values, with A. nobilis subsp. nelreichii as the sample with the highest content of TFC (11.11 ± 0.22 mg QE/g DE) when using UAE. Consequently, it could be concluded that SWE is a superior non-conventional extraction technique, and A. nobilis subsp. nerleichii presents as the most promising plant.
Keywords:
yarrow / green extraction techniques / phenolic compounds / principal component analysis / PCA / Achillea
TY - JOUR
AU - Radovanović, Katarina
AU - Gavarić, Neda
AU - Švarc-Gajić, Jaroslava
AU - Brezo-Borjan, Tanja
AU - Zlatković, Bojan
AU - Lončar, Biljana
AU - Aćimović, Milica
PY - 2023
UR - http://fiver.ifvcns.rs/handle/123456789/3342
AB - The genus Achillea has significant medical potential due to the presence of highly bioactive compounds in its chemical composition. To take advantage of plants’ biomedical potential, it is of great importance to use a proper extraction process. This study aimed to determine and compare the preliminary chemical composition of five different Achillea species extracted with two conventional (infusion and maceration) and two non-conventional (ultrasound-assisted extraction (UAE) and Subcritical water extraction (SWE)) techniques. The extracts were prepared using the previously described procedures for infusion, maceration, UAE and SWE extraction. For all extracts, the extraction yield (dry extract (DE)) was determined. The analyzed extracts were preliminarily chemically characterized spectrophotometrically in terms of total phenolic content (TPC) and total flavonoid content (TFC). The obtained results showed that non-conventional techniques delivered higher values of TPC and TFC than conventional. There is a statistically significant increase in DE and TPC content when applying SWE for all observed Achillea species. The highest DE value, 48.80 ± 1.76%, was observed for A. asplenifolia. The highest TPC values were observed after applying SWE: 93.63 ± 1.01 mg GAE/g DE for A. millefolium, and 90.12 ± 0.87 mg GAE/g DE for A. crithmifolia. The results for TFC revealed a statistically significant difference in values, with A. nobilis subsp. nelreichii as the sample with the highest content of TFC (11.11 ± 0.22 mg QE/g DE) when using UAE. Consequently, it could be concluded that SWE is a superior non-conventional extraction technique, and A. nobilis subsp. nerleichii presents as the most promising plant.
PB - Basel : MDPI
T2 - Processes - Basel
T1 - Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species
IS - 1
SP - 86
VL - 11
DO - 10.3390/pr11010086
ER -
@article{
author = "Radovanović, Katarina and Gavarić, Neda and Švarc-Gajić, Jaroslava and Brezo-Borjan, Tanja and Zlatković, Bojan and Lončar, Biljana and Aćimović, Milica",
year = "2023",
abstract = "The genus Achillea has significant medical potential due to the presence of highly bioactive compounds in its chemical composition. To take advantage of plants’ biomedical potential, it is of great importance to use a proper extraction process. This study aimed to determine and compare the preliminary chemical composition of five different Achillea species extracted with two conventional (infusion and maceration) and two non-conventional (ultrasound-assisted extraction (UAE) and Subcritical water extraction (SWE)) techniques. The extracts were prepared using the previously described procedures for infusion, maceration, UAE and SWE extraction. For all extracts, the extraction yield (dry extract (DE)) was determined. The analyzed extracts were preliminarily chemically characterized spectrophotometrically in terms of total phenolic content (TPC) and total flavonoid content (TFC). The obtained results showed that non-conventional techniques delivered higher values of TPC and TFC than conventional. There is a statistically significant increase in DE and TPC content when applying SWE for all observed Achillea species. The highest DE value, 48.80 ± 1.76%, was observed for A. asplenifolia. The highest TPC values were observed after applying SWE: 93.63 ± 1.01 mg GAE/g DE for A. millefolium, and 90.12 ± 0.87 mg GAE/g DE for A. crithmifolia. The results for TFC revealed a statistically significant difference in values, with A. nobilis subsp. nelreichii as the sample with the highest content of TFC (11.11 ± 0.22 mg QE/g DE) when using UAE. Consequently, it could be concluded that SWE is a superior non-conventional extraction technique, and A. nobilis subsp. nerleichii presents as the most promising plant.",
publisher = "Basel : MDPI",
journal = "Processes - Basel",
title = "Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species",
number = "1",
pages = "86",
volume = "11",
doi = "10.3390/pr11010086"
}
Radovanović, K., Gavarić, N., Švarc-Gajić, J., Brezo-Borjan, T., Zlatković, B., Lončar, B.,& Aćimović, M.. (2023). Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species. in Processes - Basel
Basel : MDPI., 11(1), 86.
https://doi.org/10.3390/pr11010086
Radovanović K, Gavarić N, Švarc-Gajić J, Brezo-Borjan T, Zlatković B, Lončar B, Aćimović M. Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species. in Processes - Basel. 2023;11(1):86.
doi:10.3390/pr11010086 .
Radovanović, Katarina, Gavarić, Neda, Švarc-Gajić, Jaroslava, Brezo-Borjan, Tanja, Zlatković, Bojan, Lončar, Biljana, Aćimović, Milica, "Subcritical Water Extraction as an Effective Technique for the Isolation of Phenolic Compounds of Achillea Species" in Processes - Basel, 11, no. 1 (2023):86,
https://doi.org/10.3390/pr11010086 . .
