TY  - JOUR
AU  - Aćimović, Milica
AU  - Ljujić, Jovana
AU  - Vulić, Jelena
AU  - Zheljazkov, Valtcho D
AU  - Pezo, Lato
AU  - Varga, Ana
AU  - Tumbas Šaponjac, Vesna
PY  - 2021
UR  - http://fiver.ifvcns.rs/handle/123456789/2194
AB  - H. italicum essential oil (EO) is one of the most popular ingredients utilized by the cosmetic industry, and it is also used as natural antioxidant and as a value-added ingredient in food products. The chemical composition of the EO H. italicum cultivated in Serbia was analyzed by gas chromatography–mass spectrometry. The quantitative structure–retention relationship was used to predict the retention indices of the EO constituents acquired by GC-MS data, applying five molecular descriptors selected by factor analysis and a genetic algorithm. Also, antimicrobial activity, and biological activity by four common antioxidant tests (DPPH and ABTS assays, reducing power, and beta -carotene bleaching test), and in vitro antihyperglycemic and anti-inflammatory capacities were evaluated. A total of 70 EO constituents were detected, of which 17 (8.5%) could not be identified. The H. italicum EO in this study belonged to gamma-curcumene chemotype. The coefficients of determination reached the value of 0.964, demonstrating that this model could be used for prediction purposes. All applied tests showed that H. italicum EO possesses good biological activity and an interesting chemical composition. Therefore, the EO of H. italicum grown in Serbia has a potential to be used in food, cosmetic, and pharmaceutical products.
PB  - Basel : MDPI
T2  - Agronomy
T1  - Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia
SP  - 1282
VL  - 11
DO  - 10.3390/agronomy11071282
ER  - 

@article{
author = "Aćimović, Milica and Ljujić, Jovana and Vulić, Jelena and Zheljazkov, Valtcho D and Pezo, Lato and Varga, Ana and Tumbas Šaponjac, Vesna",
year = "2021",
abstract = "H. italicum essential oil (EO) is one of the most popular ingredients utilized by the cosmetic industry, and it is also used as natural antioxidant and as a value-added ingredient in food products. The chemical composition of the EO H. italicum cultivated in Serbia was analyzed by gas chromatography–mass spectrometry. The quantitative structure–retention relationship was used to predict the retention indices of the EO constituents acquired by GC-MS data, applying five molecular descriptors selected by factor analysis and a genetic algorithm. Also, antimicrobial activity, and biological activity by four common antioxidant tests (DPPH and ABTS assays, reducing power, and beta -carotene bleaching test), and in vitro antihyperglycemic and anti-inflammatory capacities were evaluated. A total of 70 EO constituents were detected, of which 17 (8.5%) could not be identified. The H. italicum EO in this study belonged to gamma-curcumene chemotype. The coefficients of determination reached the value of 0.964, demonstrating that this model could be used for prediction purposes. All applied tests showed that H. italicum EO possesses good biological activity and an interesting chemical composition. Therefore, the EO of H. italicum grown in Serbia has a potential to be used in food, cosmetic, and pharmaceutical products.",
publisher = "Basel : MDPI",
journal = "Agronomy",
title = "Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia",
pages = "1282",
volume = "11",
doi = "10.3390/agronomy11071282"
}

Aćimović, M., Ljujić, J., Vulić, J., Zheljazkov, V. D., Pezo, L., Varga, A.,& Tumbas Šaponjac, V.. (2021). Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia. in Agronomy
Basel : MDPI., 11, 1282.
https://doi.org/10.3390/agronomy11071282

Aćimović M, Ljujić J, Vulić J, Zheljazkov VD, Pezo L, Varga A, Tumbas Šaponjac V. Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia. in Agronomy. 2021;11:1282.
doi:10.3390/agronomy11071282 .

Aćimović, Milica, Ljujić, Jovana, Vulić, Jelena, Zheljazkov, Valtcho D, Pezo, Lato, Varga, Ana, Tumbas Šaponjac, Vesna, "Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia" in Agronomy, 11 (2021):1282,
https://doi.org/10.3390/agronomy11071282 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Šeregelj, Vanja
AU  - Šovljanski, Olja
AU  - Tumbas Šaponjac, Vesna
AU  - Švarc Gajić, Jaroslava
AU  - Brezo-Borjan, Tanja
AU  - Pezo, Lato
PY  - 2021
UR  - http://fiver.ifvcns.rs/handle/123456789/2196
AB  - As the main goal of this study was the verification of Satureja kitaibelii Wierzb. ex Heuff. in form of the crude extract obtained by subcritical water extraction (SWE) technique in terms of polyphenolic composition, in vitro antioxidant capacity, antihyperglycemic, and anti-inflammatory activities as well as an antimicrobial effect against 10 microorganisms. HPLC analysis showed the presence of ten compounds in a total concentration of 89.33 mg/g of the SWE extract, and demonstrated that subcritical water polarity was the most selective for extracting syringic and caffeic acid, as well as epicatechin (37.88 18.06, and 10.04 mg/g, respectively), while flavonoids like rutin, luteolin, and apigenin were present in low concentration (<2 mg/g). Results of antioxidant activity assays revealed that superoxide anion and ABTS•+ radical models expressed the highest scavenging abilities (437.35 and 412.09 μmol TE/g, respectively), followed by lipid radicals (69.61 μmol TE/g), and DPPH• (32.28 μmol TE/g), while in the case of ferric ion reducing ability was noted a high value (118.19 μmol TE/g). S. kitaibelii SWE was less efficient in the antihyperglycemic assay (AhgA = 30.72 %), but the high antiinflammatory activity of S. kitaibelii SWE was observed (30.35 %). The antimicrobial activity was demonstrated against Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, Listeria monocytogenes as well as Saccharomyces cerevisiae, Candida albicans, and Aspergillus brasiliensis through antimicrobial screening, minimal inhibitory concentration, and pharmacodynamics study.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - In vitro antioxidant, antihyperglycemic, anti-inflammatory, and antimicrobial activity of Satureja kitaibelii Wierzb. ex Heuff. subcritical water extract
SP  - 113672
VL  - 169
DO  - 10.1016/j.indcrop.2021.113672
ER  - 

@article{
author = "Aćimović, Milica and Šeregelj, Vanja and Šovljanski, Olja and Tumbas Šaponjac, Vesna and Švarc Gajić, Jaroslava and Brezo-Borjan, Tanja and Pezo, Lato",
year = "2021",
abstract = "As the main goal of this study was the verification of Satureja kitaibelii Wierzb. ex Heuff. in form of the crude extract obtained by subcritical water extraction (SWE) technique in terms of polyphenolic composition, in vitro antioxidant capacity, antihyperglycemic, and anti-inflammatory activities as well as an antimicrobial effect against 10 microorganisms. HPLC analysis showed the presence of ten compounds in a total concentration of 89.33 mg/g of the SWE extract, and demonstrated that subcritical water polarity was the most selective for extracting syringic and caffeic acid, as well as epicatechin (37.88 18.06, and 10.04 mg/g, respectively), while flavonoids like rutin, luteolin, and apigenin were present in low concentration (<2 mg/g). Results of antioxidant activity assays revealed that superoxide anion and ABTS•+ radical models expressed the highest scavenging abilities (437.35 and 412.09 μmol TE/g, respectively), followed by lipid radicals (69.61 μmol TE/g), and DPPH• (32.28 μmol TE/g), while in the case of ferric ion reducing ability was noted a high value (118.19 μmol TE/g). S. kitaibelii SWE was less efficient in the antihyperglycemic assay (AhgA = 30.72 %), but the high antiinflammatory activity of S. kitaibelii SWE was observed (30.35 %). The antimicrobial activity was demonstrated against Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, Listeria monocytogenes as well as Saccharomyces cerevisiae, Candida albicans, and Aspergillus brasiliensis through antimicrobial screening, minimal inhibitory concentration, and pharmacodynamics study.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "In vitro antioxidant, antihyperglycemic, anti-inflammatory, and antimicrobial activity of Satureja kitaibelii Wierzb. ex Heuff. subcritical water extract",
pages = "113672",
volume = "169",
doi = "10.1016/j.indcrop.2021.113672"
}

Aćimović, M., Šeregelj, V., Šovljanski, O., Tumbas Šaponjac, V., Švarc Gajić, J., Brezo-Borjan, T.,& Pezo, L.. (2021). In vitro antioxidant, antihyperglycemic, anti-inflammatory, and antimicrobial activity of Satureja kitaibelii Wierzb. ex Heuff. subcritical water extract. in Industrial Crops and Products
Elsevier., 169, 113672.
https://doi.org/10.1016/j.indcrop.2021.113672

Aćimović M, Šeregelj V, Šovljanski O, Tumbas Šaponjac V, Švarc Gajić J, Brezo-Borjan T, Pezo L. In vitro antioxidant, antihyperglycemic, anti-inflammatory, and antimicrobial activity of Satureja kitaibelii Wierzb. ex Heuff. subcritical water extract. in Industrial Crops and Products. 2021;169:113672.
doi:10.1016/j.indcrop.2021.113672 .

Aćimović, Milica, Šeregelj, Vanja, Šovljanski, Olja, Tumbas Šaponjac, Vesna, Švarc Gajić, Jaroslava, Brezo-Borjan, Tanja, Pezo, Lato, "In vitro antioxidant, antihyperglycemic, anti-inflammatory, and antimicrobial activity of Satureja kitaibelii Wierzb. ex Heuff. subcritical water extract" in Industrial Crops and Products, 169 (2021):113672,
https://doi.org/10.1016/j.indcrop.2021.113672 . .