TY  - JOUR
AU  - Lazarević, Jovan
AU  - Aćimović, Milica
AU  - Đurović-Pejčev, Rada
AU  - Lončar, Biljana
AU  - Vukić, Vladimir
AU  - Pezo, Lato
AU  - Roljević Nikolić, Svetlana
AU  - Vrbničanin, Sava
AU  - Božić, Dragana
PY  - 2024
UR  - http://fiver.ifvcns.rs/handle/123456789/4645
AB  - The present study aimed to evaluate garden angelica (Angelica archangelica L.) root essential oil composition modulated by weed management techniques. Eight different treatments, including weed free (manual weeding removal), weedy check (untreated control), two organic mulches: sawdust and straw, two physical methods mulches: agro-textile foil and silver-brown foil, and two herbicides: Metamitron and Aclonifen, were employed in open field growing A. archangelica. The composition of the root essential oil was analysed by gas chromatography-mass spectrometry. The results revealed that main compounds in A. archangelica root essential oil was β-phellandrene (6.7–17.2%) and α-pinene (7.8–17.2%), followed by δ-3-carene (4.2–14.1%) and p-cymene (6.4–10.5%). According to molecular docking results and binding energy calculations, there are several compounds present in A. archangelica essential oil that could have modulatory effects on inflammatory pathways. However, α-pinene, osthol, α-terpinol, p-cymene, and β-phellandrene seem to be the most effective anti-inflammatory compounds from the examined oil. Application of herbicides in weed management significantly influences the accumulation α-pinene as a dominant compound in A. archangelica essential oil, while β-phellandrene dominant in straw weed management. Moreover, α-terpineol was the most abundant in sawdust weed management treatment, while osthol was dominant in weed free treatment. In conclusion, organic mulches, especially sawdust, can be recommended for the production of A. archangelica roots with the highest essential oil content, while straw as an organic mulch gives the highest concentration of main compounds with promising anti-inflammatory potential.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Linking weed control techniques to anti-inflammatory potential: Comparative analysis of Angelica archangelica L. root essential oil profiles
SP  - 118656
VL  - 216
DO  - 10.1016/j.indcrop.2024.118656
ER  - 

@article{
author = "Lazarević, Jovan and Aćimović, Milica and Đurović-Pejčev, Rada and Lončar, Biljana and Vukić, Vladimir and Pezo, Lato and Roljević Nikolić, Svetlana and Vrbničanin, Sava and Božić, Dragana",
year = "2024",
abstract = "The present study aimed to evaluate garden angelica (Angelica archangelica L.) root essential oil composition modulated by weed management techniques. Eight different treatments, including weed free (manual weeding removal), weedy check (untreated control), two organic mulches: sawdust and straw, two physical methods mulches: agro-textile foil and silver-brown foil, and two herbicides: Metamitron and Aclonifen, were employed in open field growing A. archangelica. The composition of the root essential oil was analysed by gas chromatography-mass spectrometry. The results revealed that main compounds in A. archangelica root essential oil was β-phellandrene (6.7–17.2%) and α-pinene (7.8–17.2%), followed by δ-3-carene (4.2–14.1%) and p-cymene (6.4–10.5%). According to molecular docking results and binding energy calculations, there are several compounds present in A. archangelica essential oil that could have modulatory effects on inflammatory pathways. However, α-pinene, osthol, α-terpinol, p-cymene, and β-phellandrene seem to be the most effective anti-inflammatory compounds from the examined oil. Application of herbicides in weed management significantly influences the accumulation α-pinene as a dominant compound in A. archangelica essential oil, while β-phellandrene dominant in straw weed management. Moreover, α-terpineol was the most abundant in sawdust weed management treatment, while osthol was dominant in weed free treatment. In conclusion, organic mulches, especially sawdust, can be recommended for the production of A. archangelica roots with the highest essential oil content, while straw as an organic mulch gives the highest concentration of main compounds with promising anti-inflammatory potential.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Linking weed control techniques to anti-inflammatory potential: Comparative analysis of Angelica archangelica L. root essential oil profiles",
pages = "118656",
volume = "216",
doi = "10.1016/j.indcrop.2024.118656"
}

Lazarević, J., Aćimović, M., Đurović-Pejčev, R., Lončar, B., Vukić, V., Pezo, L., Roljević Nikolić, S., Vrbničanin, S.,& Božić, D.. (2024). Linking weed control techniques to anti-inflammatory potential: Comparative analysis of Angelica archangelica L. root essential oil profiles. in Industrial Crops and Products
Elsevier., 216, 118656.
https://doi.org/10.1016/j.indcrop.2024.118656

Lazarević J, Aćimović M, Đurović-Pejčev R, Lončar B, Vukić V, Pezo L, Roljević Nikolić S, Vrbničanin S, Božić D. Linking weed control techniques to anti-inflammatory potential: Comparative analysis of Angelica archangelica L. root essential oil profiles. in Industrial Crops and Products. 2024;216:118656.
doi:10.1016/j.indcrop.2024.118656 .

Lazarević, Jovan, Aćimović, Milica, Đurović-Pejčev, Rada, Lončar, Biljana, Vukić, Vladimir, Pezo, Lato, Roljević Nikolić, Svetlana, Vrbničanin, Sava, Božić, Dragana, "Linking weed control techniques to anti-inflammatory potential: Comparative analysis of Angelica archangelica L. root essential oil profiles" in Industrial Crops and Products, 216 (2024):118656,
https://doi.org/10.1016/j.indcrop.2024.118656 . .

TY  - JOUR
AU  - Aćimović, Milica
AU  - Semerdijeva, Ivanka
AU  - Zheljazkov, Valtcho
AU  - Rat, Milica
AU  - Stanković Jeremić, Jovana
AU  - Lončar, Biljana
AU  - Vukić, Vladimir
AU  - Radovanović, Katarina
AU  - Gavarić, Neda
AU  - Pezo, Lato
PY  - 2023
UR  - http://fiver.ifvcns.rs/handle/123456789/4054
AB  - This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile.
PB  - Elsevier
T2  - Biochemical Systematics and Ecology
T1  - Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm
SP  - 104679
VL  - 110
DO  - 10.1016/j.bse.2023.104679
ER  - 

@article{
author = "Aćimović, Milica and Semerdijeva, Ivanka and Zheljazkov, Valtcho and Rat, Milica and Stanković Jeremić, Jovana and Lončar, Biljana and Vukić, Vladimir and Radovanović, Katarina and Gavarić, Neda and Pezo, Lato",
year = "2023",
abstract = "This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile.",
publisher = "Elsevier",
journal = "Biochemical Systematics and Ecology",
title = "Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm",
pages = "104679",
volume = "110",
doi = "10.1016/j.bse.2023.104679"
}

Aćimović, M., Semerdijeva, I., Zheljazkov, V., Rat, M., Stanković Jeremić, J., Lončar, B., Vukić, V., Radovanović, K., Gavarić, N.,& Pezo, L.. (2023). Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm. in Biochemical Systematics and Ecology
Elsevier., 110, 104679.
https://doi.org/10.1016/j.bse.2023.104679

Aćimović M, Semerdijeva I, Zheljazkov V, Rat M, Stanković Jeremić J, Lončar B, Vukić V, Radovanović K, Gavarić N, Pezo L. Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm. in Biochemical Systematics and Ecology. 2023;110:104679.
doi:10.1016/j.bse.2023.104679 .

Aćimović, Milica, Semerdijeva, Ivanka, Zheljazkov, Valtcho, Rat, Milica, Stanković Jeremić, Jovana, Lončar, Biljana, Vukić, Vladimir, Radovanović, Katarina, Gavarić, Neda, Pezo, Lato, "Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm" in Biochemical Systematics and Ecology, 110 (2023):104679,
https://doi.org/10.1016/j.bse.2023.104679 . .