TY  - JOUR
AU  - Mitrović, Ivana
AU  - Vučurović, Damjan
AU  - Al-Ani, Laith Khalil Tawfeeq
AU  - Mitrović, Bojan
AU  - Bajić, Bojana
AU  - Dodić, Siniša
AU  - Tančić-Živanov, Sonja
PY  - 2023
UR  - http://fiver.ifvcns.rs/handle/123456789/4532
AB  - In order to be competitive on the market, the production of biopreparations needs to be optimized, modelled, and assessed in the early stages of its development. The aim of this paper was to optimize medium for the production of Trichoderma harzianum K179 biocontrol agent, to analyze its kinetics at enlarged laboratory scale and finally economic analysis of the production of this high-value product through simulation modelling. The results showed that the bioprocess of T. harzianum K179 bioagent production in a laboratory bioreactor on the medium with optimal composition (dextrose 10 g l−1, soy flour 6.87 g l−1, K2HPO4 1.51 g l−1, KCl 0.5 g l−1, and MgSO4 × 7H2O 0.5 g l−1), at stirring speed of 1.75 × g and aeration intensity of 1.5 vvm, can be shortened from 96 to 36 h. The results of bioprocess economic analysis showed that with a 25-year project lifetime and an investment payback time of 7.58 years, this project represents an economically viable system.
PB  - Oxford : Oxford University Press
T2  - Journal of Applied Microbiology
T1  - Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development
IS  - 6
SP  - lxad115
VL  - 134
DO  - 10.1093/jambio/lxad115
ER  - 

@article{
author = "Mitrović, Ivana and Vučurović, Damjan and Al-Ani, Laith Khalil Tawfeeq and Mitrović, Bojan and Bajić, Bojana and Dodić, Siniša and Tančić-Živanov, Sonja",
year = "2023",
abstract = "In order to be competitive on the market, the production of biopreparations needs to be optimized, modelled, and assessed in the early stages of its development. The aim of this paper was to optimize medium for the production of Trichoderma harzianum K179 biocontrol agent, to analyze its kinetics at enlarged laboratory scale and finally economic analysis of the production of this high-value product through simulation modelling. The results showed that the bioprocess of T. harzianum K179 bioagent production in a laboratory bioreactor on the medium with optimal composition (dextrose 10 g l−1, soy flour 6.87 g l−1, K2HPO4 1.51 g l−1, KCl 0.5 g l−1, and MgSO4 × 7H2O 0.5 g l−1), at stirring speed of 1.75 × g and aeration intensity of 1.5 vvm, can be shortened from 96 to 36 h. The results of bioprocess economic analysis showed that with a 25-year project lifetime and an investment payback time of 7.58 years, this project represents an economically viable system.",
publisher = "Oxford : Oxford University Press",
journal = "Journal of Applied Microbiology",
title = "Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development",
number = "6",
pages = "lxad115",
volume = "134",
doi = "10.1093/jambio/lxad115"
}

Mitrović, I., Vučurović, D., Al-Ani, L. K. T., Mitrović, B., Bajić, B., Dodić, S.,& Tančić-Živanov, S.. (2023). Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development. in Journal of Applied Microbiology
Oxford : Oxford University Press., 134(6), lxad115.
https://doi.org/10.1093/jambio/lxad115

Mitrović I, Vučurović D, Al-Ani LKT, Mitrović B, Bajić B, Dodić S, Tančić-Živanov S. Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development. in Journal of Applied Microbiology. 2023;134(6):lxad115.
doi:10.1093/jambio/lxad115 .

Mitrović, Ivana, Vučurović, Damjan, Al-Ani, Laith Khalil Tawfeeq, Mitrović, Bojan, Bajić, Bojana, Dodić, Siniša, Tančić-Živanov, Sonja, "Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development" in Journal of Applied Microbiology, 134, no. 6 (2023):lxad115,
https://doi.org/10.1093/jambio/lxad115 . .

TY  - JOUR
AU  - Mitrović, Ivana
AU  - Vučurović, Damjan
AU  - Al-Ani, Laith Khalil Tawfeeq
AU  - Mitrović, Bojan
AU  - Bajić, Bojana
AU  - Dodić, Siniša
AU  - Tančić-Živanov, Sonja
PY  - 2023
UR  - http://fiver.ifvcns.rs/handle/123456789/3979
AB  - In order to be competitive on the market, the production of biopreparations needs to be optimized, modelled, and assessed in the early stages of its development. The aim of this paper was to optimize medium for the production of Trichoderma harzianum K179 biocontrol agent, to analyze its kinetics at enlarged laboratory scale and finally economic analysis of the production of this high-value product through simulation modelling. The results showed that the bioprocess of T. harzianum K179 bioagent production in a laboratory bioreactor on the medium with optimal composition (dextrose 10 g l−1, soy flour 6.87 g l−1, K2HPO4 1.51 g l−1, KCl 0.5 g l−1, and MgSO4 × 7H2O 0.5 g l−1), at stirring speed of 1.75 × g and aeration intensity of 1.5 vvm, can be shortened from 96 to 36 h. The results of bioprocess economic analysis showed that with a 25-year project lifetime and an investment payback time of 7.58 years, this project represents an economically viable system.
PB  - Oxford : Oxford University Press
T2  - Journal of Applied Microbiology
T1  - Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development
IS  - 6
SP  - lxad115
VL  - 134
DO  - 10.1093/jambio/lxad115
ER  - 

@article{
author = "Mitrović, Ivana and Vučurović, Damjan and Al-Ani, Laith Khalil Tawfeeq and Mitrović, Bojan and Bajić, Bojana and Dodić, Siniša and Tančić-Živanov, Sonja",
year = "2023",
abstract = "In order to be competitive on the market, the production of biopreparations needs to be optimized, modelled, and assessed in the early stages of its development. The aim of this paper was to optimize medium for the production of Trichoderma harzianum K179 biocontrol agent, to analyze its kinetics at enlarged laboratory scale and finally economic analysis of the production of this high-value product through simulation modelling. The results showed that the bioprocess of T. harzianum K179 bioagent production in a laboratory bioreactor on the medium with optimal composition (dextrose 10 g l−1, soy flour 6.87 g l−1, K2HPO4 1.51 g l−1, KCl 0.5 g l−1, and MgSO4 × 7H2O 0.5 g l−1), at stirring speed of 1.75 × g and aeration intensity of 1.5 vvm, can be shortened from 96 to 36 h. The results of bioprocess economic analysis showed that with a 25-year project lifetime and an investment payback time of 7.58 years, this project represents an economically viable system.",
publisher = "Oxford : Oxford University Press",
journal = "Journal of Applied Microbiology",
title = "Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development",
number = "6",
pages = "lxad115",
volume = "134",
doi = "10.1093/jambio/lxad115"
}

Mitrović, I., Vučurović, D., Al-Ani, L. K. T., Mitrović, B., Bajić, B., Dodić, S.,& Tančić-Živanov, S.. (2023). Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development. in Journal of Applied Microbiology
Oxford : Oxford University Press., 134(6), lxad115.
https://doi.org/10.1093/jambio/lxad115

Mitrović I, Vučurović D, Al-Ani LKT, Mitrović B, Bajić B, Dodić S, Tančić-Živanov S. Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development. in Journal of Applied Microbiology. 2023;134(6):lxad115.
doi:10.1093/jambio/lxad115 .

Mitrović, Ivana, Vučurović, Damjan, Al-Ani, Laith Khalil Tawfeeq, Mitrović, Bojan, Bajić, Bojana, Dodić, Siniša, Tančić-Živanov, Sonja, "Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development" in Journal of Applied Microbiology, 134, no. 6 (2023):lxad115,
https://doi.org/10.1093/jambio/lxad115 . .

TY  - JOUR
AU  - Mitrović, Ivana
AU  - Vučurović, Damjan
AU  - Al-Ani, Laith Khalil Tawfeeq
AU  - Mitrović, Bojan
AU  - Bajić, Bojana
AU  - Dodić, Siniša
PY  - 2023
UR  - http://fiver.ifvcns.rs/handle/123456789/4056
AB  - In order to be competitive on the market, the production of biopreparations needs to be optimized, modelled, and assessed in the early stages of its development. The aim of this paper was to optimize medium for the production of Trichoderma harzianum K179 biocontrol agent, to analyze its kinetics at enlarged laboratory scale and finally economic analysis of the production of this high-value product through simulation modelling. Complete analysis of the bioprocess of T. harzianum K179 biocontrol agent production showed that the biologically produced preparation can be competitive on the market with synthetic preparations.
PB  - Society for Applied Microbiology
PB  - Oxford : Oxford University Press
T2  - Journal of Applied Microbiology
T1  - Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development
IS  - 6
SP  - lxad115
VL  - 134
DO  - 10.1093/jambio/lxad115
ER  - 

@article{
author = "Mitrović, Ivana and Vučurović, Damjan and Al-Ani, Laith Khalil Tawfeeq and Mitrović, Bojan and Bajić, Bojana and Dodić, Siniša",
year = "2023",
abstract = "In order to be competitive on the market, the production of biopreparations needs to be optimized, modelled, and assessed in the early stages of its development. The aim of this paper was to optimize medium for the production of Trichoderma harzianum K179 biocontrol agent, to analyze its kinetics at enlarged laboratory scale and finally economic analysis of the production of this high-value product through simulation modelling. Complete analysis of the bioprocess of T. harzianum K179 biocontrol agent production showed that the biologically produced preparation can be competitive on the market with synthetic preparations.",
publisher = "Society for Applied Microbiology, Oxford : Oxford University Press",
journal = "Journal of Applied Microbiology",
title = "Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development",
number = "6",
pages = "lxad115",
volume = "134",
doi = "10.1093/jambio/lxad115"
}

Mitrović, I., Vučurović, D., Al-Ani, L. K. T., Mitrović, B., Bajić, B.,& Dodić, S.. (2023). Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development. in Journal of Applied Microbiology
Society for Applied Microbiology., 134(6), lxad115.
https://doi.org/10.1093/jambio/lxad115

Mitrović I, Vučurović D, Al-Ani LKT, Mitrović B, Bajić B, Dodić S. Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development. in Journal of Applied Microbiology. 2023;134(6):lxad115.
doi:10.1093/jambio/lxad115 .

Mitrović, Ivana, Vučurović, Damjan, Al-Ani, Laith Khalil Tawfeeq, Mitrović, Bojan, Bajić, Bojana, Dodić, Siniša, "Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development" in Journal of Applied Microbiology, 134, no. 6 (2023):lxad115,
https://doi.org/10.1093/jambio/lxad115 . .