Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm
No Thumbnail
Authors
Aćimović, MilicaSemerdijeva, Ivanka
Zheljazkov, Valtcho
Rat, Milica
Stanković Jeremić, Jovana
Lončar, Biljana
Vukić, Vladimir
Radovanović, Katarina
Gavarić, Neda
Pezo, Lato
Article (Published version)
Metadata
Show full item recordAbstract
This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile.
Keywords:
endemic species / Achillea / hydrodistillation / principal component analysis / volatile compounds / essential oils / in silico analysis / Achillea clypeolata Sm / Balkan / essential oil compositionSource:
Biochemical Systematics and Ecology, 2023, 110, 104679-Publisher:
- Elsevier
Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200032 (Institute of Field and Vegetable Crops, Novi Sad) (RS-MESTD-inst-2020-200032)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200114 (University of Novi Sad, Faculty of Medicine) (RS-MESTD-inst-2020-200114)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200134 (University of Novi Sad, Faculty of Technology) (RS-MESTD-inst-2020-200134)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200051 (Institute of General and Physical Chemistry, Belgrade) (RS-MESTD-inst-2020-200051)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200026 (University of Belgrade, Institute of Chemistry, Technology and Metallurgy - IChTM) (RS-MESTD-inst-2020-200026)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200125 (University of Novi Sad, Faculty of Science) (RS-MESTD-inst-2020-200125)
Collections
Institution/Community
FiVeRTY - JOUR AU - Aćimović, Milica AU - Semerdijeva, Ivanka AU - Zheljazkov, Valtcho AU - Rat, Milica AU - Stanković Jeremić, Jovana AU - Lončar, Biljana AU - Vukić, Vladimir AU - Radovanović, Katarina AU - Gavarić, Neda AU - Pezo, Lato PY - 2023 UR - http://fiver.ifvcns.rs/handle/123456789/4054 AB - This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile. PB - Elsevier T2 - Biochemical Systematics and Ecology T1 - Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm SP - 104679 VL - 110 DO - 10.1016/j.bse.2023.104679 ER -
@article{ author = "Aćimović, Milica and Semerdijeva, Ivanka and Zheljazkov, Valtcho and Rat, Milica and Stanković Jeremić, Jovana and Lončar, Biljana and Vukić, Vladimir and Radovanović, Katarina and Gavarić, Neda and Pezo, Lato", year = "2023", abstract = "This research investigated a Balkan endemic species, Achillea clypeolata, collected from two locations (Dobrostan and Ivaylovgrad) in Bulgaria and two locations (Ozren and Rtanj) in Serbia. The goal was to compare the essential oil (EO) of A. clypeolata from these four localities. The EO was isolated from dry aboveground plant parts by hydrodistillation, and the identification of the EO constituents was carried out by GC-MS analyses. Principal Component Analysis (PCA), correlation analysis, and an unrooted cluster tree were used to define distinctions in the presence of volatile compounds in A. clypeolata EO. Results showed that A. clypeolata of Serbian origin (Ozren and Rtanj) contained 1,8-cineole as the main constituent, and belonged to the previously described 1,8-cineole as a dominant compound in the EO profile.", publisher = "Elsevier", journal = "Biochemical Systematics and Ecology", title = "Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm", pages = "104679", volume = "110", doi = "10.1016/j.bse.2023.104679" }
Aćimović, M., Semerdijeva, I., Zheljazkov, V., Rat, M., Stanković Jeremić, J., Lončar, B., Vukić, V., Radovanović, K., Gavarić, N.,& Pezo, L.. (2023). Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm. in Biochemical Systematics and Ecology Elsevier., 110, 104679. https://doi.org/10.1016/j.bse.2023.104679
Aćimović M, Semerdijeva I, Zheljazkov V, Rat M, Stanković Jeremić J, Lončar B, Vukić V, Radovanović K, Gavarić N, Pezo L. Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm. in Biochemical Systematics and Ecology. 2023;110:104679. doi:10.1016/j.bse.2023.104679 .
Aćimović, Milica, Semerdijeva, Ivanka, Zheljazkov, Valtcho, Rat, Milica, Stanković Jeremić, Jovana, Lončar, Biljana, Vukić, Vladimir, Radovanović, Katarina, Gavarić, Neda, Pezo, Lato, "Variation in the essential oil composition and in silico analysis of anti-inflammatory potential of Balkan endemic species Achillea clypeolata Sm" in Biochemical Systematics and Ecology, 110 (2023):104679, https://doi.org/10.1016/j.bse.2023.104679 . .