Marrubium vulgareL.: A Phytochemical and Pharmacological Overview
2020
Authors
Aćimović, MilicaJeremić, Katarina
Salaj, Nebojša
Gavarić, Neda
Kiprovski, Biljana
Sikora, Vladimir
Zeremski, Tijana
Article (Published version)
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Marrubium vulgareis a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies,M. vulgareacts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+ bacteria, fungi, herpes simplex virus, and parasites such asToxoplasma gondii,Trichomonas vaginalis, andPlasmodium berghei-bergheiwas recorded. Additionally, it could be used as a chicken lice repellent, herbicide, and natural insecticide against mosquito larvae and natural molluscicide. In veterinary medicine,M. vulgarecan be used as an anthelmintic against the eggs and larvae of bovine strongyles parasites, and as an antibi...otic against bovine mastitis caused by resistant bacterial strains. Due to the mentioned benefits, there is a tendency for the cultivation ofM. vulgarein order to ensure high-quality raw material, but more firm scientific evidence and well-designed clinical trials are necessary for the well-established use ofM. vulgareherb and its preparations.
Keywords:
bioactivity / horehound / medicinal properties / morphology / marrubinSource:
Molecules, 2020, 25, 12Publisher:
- Basel : MDPI
Funding / projects:
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200032 (Institute of Field and Vegetable Crops, Novi Sad) (RS-MESTD-inst-2020-200032)
DOI: 10.3390/molecules25122898
ISSN: 1420-3049
PubMed: 32599693
WoS: 000550141700001
Scopus: 2-s2.0-85087421924
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FiVeRTY - JOUR AU - Aćimović, Milica AU - Jeremić, Katarina AU - Salaj, Nebojša AU - Gavarić, Neda AU - Kiprovski, Biljana AU - Sikora, Vladimir AU - Zeremski, Tijana PY - 2020 UR - http://fiver.ifvcns.rs/handle/123456789/2019 AB - Marrubium vulgareis a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies,M. vulgareacts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+ bacteria, fungi, herpes simplex virus, and parasites such asToxoplasma gondii,Trichomonas vaginalis, andPlasmodium berghei-bergheiwas recorded. Additionally, it could be used as a chicken lice repellent, herbicide, and natural insecticide against mosquito larvae and natural molluscicide. In veterinary medicine,M. vulgarecan be used as an anthelmintic against the eggs and larvae of bovine strongyles parasites, and as an antibiotic against bovine mastitis caused by resistant bacterial strains. Due to the mentioned benefits, there is a tendency for the cultivation ofM. vulgarein order to ensure high-quality raw material, but more firm scientific evidence and well-designed clinical trials are necessary for the well-established use ofM. vulgareherb and its preparations. PB - Basel : MDPI T2 - Molecules T1 - Marrubium vulgareL.: A Phytochemical and Pharmacological Overview IS - 12 VL - 25 DO - 10.3390/molecules25122898 ER -
@article{ author = "Aćimović, Milica and Jeremić, Katarina and Salaj, Nebojša and Gavarić, Neda and Kiprovski, Biljana and Sikora, Vladimir and Zeremski, Tijana", year = "2020", abstract = "Marrubium vulgareis a plant with high bioactive potential. It contains marrubiin, a labdane diterpene that is characteristic for this genus, as well as a complex mixture of phenolic compounds. According to numerous studies,M. vulgareacts as a good antioxidant agent, and due to this, it could potentially be useful in treatments of cancer, diabetes mellitus, and liver diseases. In addition, its anti-inflammatory, wound-healing, antihypertensive, hypolipidemic, and sedative potential are discussed. Apart from that, its antimicrobial activity, especially against Gram+ bacteria, fungi, herpes simplex virus, and parasites such asToxoplasma gondii,Trichomonas vaginalis, andPlasmodium berghei-bergheiwas recorded. Additionally, it could be used as a chicken lice repellent, herbicide, and natural insecticide against mosquito larvae and natural molluscicide. In veterinary medicine,M. vulgarecan be used as an anthelmintic against the eggs and larvae of bovine strongyles parasites, and as an antibiotic against bovine mastitis caused by resistant bacterial strains. Due to the mentioned benefits, there is a tendency for the cultivation ofM. vulgarein order to ensure high-quality raw material, but more firm scientific evidence and well-designed clinical trials are necessary for the well-established use ofM. vulgareherb and its preparations.", publisher = "Basel : MDPI", journal = "Molecules", title = "Marrubium vulgareL.: A Phytochemical and Pharmacological Overview", number = "12", volume = "25", doi = "10.3390/molecules25122898" }
Aćimović, M., Jeremić, K., Salaj, N., Gavarić, N., Kiprovski, B., Sikora, V.,& Zeremski, T.. (2020). Marrubium vulgareL.: A Phytochemical and Pharmacological Overview. in Molecules Basel : MDPI., 25(12). https://doi.org/10.3390/molecules25122898
Aćimović M, Jeremić K, Salaj N, Gavarić N, Kiprovski B, Sikora V, Zeremski T. Marrubium vulgareL.: A Phytochemical and Pharmacological Overview. in Molecules. 2020;25(12). doi:10.3390/molecules25122898 .
Aćimović, Milica, Jeremić, Katarina, Salaj, Nebojša, Gavarić, Neda, Kiprovski, Biljana, Sikora, Vladimir, Zeremski, Tijana, "Marrubium vulgareL.: A Phytochemical and Pharmacological Overview" in Molecules, 25, no. 12 (2020), https://doi.org/10.3390/molecules25122898 . .