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Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development
dc.creator | Mitrović, Ivana | |
dc.creator | Vučurović, Damjan | |
dc.creator | Al-Ani, Laith Khalil Tawfeeq | |
dc.creator | Mitrović, Bojan | |
dc.creator | Bajić, Bojana | |
dc.creator | Dodić, Siniša | |
dc.creator | Tančić-Živanov, Sonja | |
dc.date.accessioned | 2024-04-22T09:25:04Z | |
dc.date.available | 2024-07-01 | |
dc.date.issued | 2023 | |
dc.identifier.issn | 1365-2672 | |
dc.identifier.uri | http://fiver.ifvcns.rs/handle/123456789/4532 | |
dc.description.abstract | In order to be competitive on the market, the production of biopreparations needs to be optimized, modelled, and assessed in the early stages of its development. The aim of this paper was to optimize medium for the production of Trichoderma harzianum K179 biocontrol agent, to analyze its kinetics at enlarged laboratory scale and finally economic analysis of the production of this high-value product through simulation modelling. The results showed that the bioprocess of T. harzianum K179 bioagent production in a laboratory bioreactor on the medium with optimal composition (dextrose 10 g l−1, soy flour 6.87 g l−1, K2HPO4 1.51 g l−1, KCl 0.5 g l−1, and MgSO4 × 7H2O 0.5 g l−1), at stirring speed of 1.75 × g and aeration intensity of 1.5 vvm, can be shortened from 96 to 36 h. The results of bioprocess economic analysis showed that with a 25-year project lifetime and an investment payback time of 7.58 years, this project represents an economically viable system. | sr |
dc.language.iso | en | sr |
dc.publisher | Oxford : Oxford University Press | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200134/RS// | sr |
dc.relation | APV 142-451-3213/2020-03 financed by the Provincial Secretariat for Higher Education and Scientific Research, AP Vojvodina | sr |
dc.rights | embargoedAccess | sr |
dc.source | Journal of Applied Microbiology | sr |
dc.subject | biocontrol | sr |
dc.subject | bioprocessing | sr |
dc.subject | optimization | sr |
dc.subject | bioproducts | sr |
dc.subject | modelling | sr |
dc.subject | Trichoderma harzianum | sr |
dc.subject | maize | sr |
dc.subject | disease control | sr |
dc.title | Production of Trichoderma harzianum K179 bioagent for maize diseases control: complete laboratory stage bioprocess development | sr |
dc.type | article | sr |
dc.rights.license | ARR | sr |
dc.citation.issue | 6 | |
dc.citation.spage | lxad115 | |
dc.citation.volume | 134 | |
dc.description.other | This is a pre-copyedited, author-produced version of an article accepted for publication in Journal of Applied Microbiology following peer review and will be open after 1 July 2024. The version of record is available online at: [https://academic.oup.com/jambio/article/abstract/134/6/lxad115/7190631?redirectedFrom=fulltext] | sr |
dc.description.other | The published version record in this repository is available at: [http://fiver.ifvcns.rs/handle/123456789/3979] | |
dc.identifier.doi | 10.1093/jambio/lxad115 | |
dc.type.version | acceptedVersion | sr |