The effect of long term exposure to cadmium on Ostrinia nubilalis growth, development, survival rate and oxidative status
Authors
Vukašinović, Elvira L.Celić, Tatjana
Kojić, Danijela
Franeta, Filip
Milić, Stanko
Ninkov, Jordana
Blagojević, Dusko
Purać, Jelena
Article (Accepted Version)
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In this study the effect of long term exposure to cadmium (Cd) on Ostrinia nubilalis larval growth, development, survival rate and oxidative status was analyzed. Newly hatched first instar - L1 larvae were reared on a Cd contaminated diet until the larvae reached the final, fifth instar - L5 or developed into pupae. In total, six experimental groups, five treatments (concentrations of Cd in fresh diet: Cd I: 0.73, Cd II: 3.70, Cd III: 6.85, Cd IV: 41.71 and Cd V: 77.53 mg kg(-1)) and a control group (C) were set up. The results of the experiment showed that exposure to higher concentrations of Cd (41.71 and 77.53 mg kg(-1)) had a significant influence on development and redox status of O. nubilalis larvae: (1) the development rate was strongly reduced resulting in a prolonged pupation time; (2) the survival rate of larvae was prominently lower; (3) bioaccumulation factor (measured in pupae) was reduced which indicated that larvae could accumulate Cd to a certain level; (4) the level of... the lipid peroxidation was significantly higher, which points to oxidative damage; (5) the expression of Mtn was significantly up-regulated while Cat and GPx genes down-regulated. In conclusion, long term exposure to dietary Cd in a concentration of 41.7 mg kg(-1) and higher, induced oxidative stress and slowed down growth and development of O. nubilalis larvae.
Keywords:
Heavy metals / Bioaccumulation / Larvae / Pupae / Gene expression / MDASource:
Chemosphere, 2020, 243, 125375-Publisher:
- Oxford : Pergamon-Elsevier Science Ltd.
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Note:
- This is the peer-reviewed version of the article: Vukašinović Elvira L., Celić Tatjana, Kojić Danijela, Franeta Filip, Milić Stanko, Ninkov Jordana, Blagojević Dusko, Purać Jelena, "The effect of long term exposure to cadmium on Ostrinia nubilalis growth, development, survival rate and oxidative status" Chemosphere, 243 (2020), https://doi.org/10.1016/j.chemosphere.2019.125375
Related info:
DOI: 10.1016/j.chemosphere.2019.125375
ISSN: 0045-6535
PubMed: 31778918
WoS: 000512221100058
Scopus: 2-s2.0-85075345822
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FiVeRTY - JOUR AU - Vukašinović, Elvira L. AU - Celić, Tatjana AU - Kojić, Danijela AU - Franeta, Filip AU - Milić, Stanko AU - Ninkov, Jordana AU - Blagojević, Dusko AU - Purać, Jelena PY - 2020 UR - http://fiver.ifvcns.rs/handle/123456789/2144 AB - In this study the effect of long term exposure to cadmium (Cd) on Ostrinia nubilalis larval growth, development, survival rate and oxidative status was analyzed. Newly hatched first instar - L1 larvae were reared on a Cd contaminated diet until the larvae reached the final, fifth instar - L5 or developed into pupae. In total, six experimental groups, five treatments (concentrations of Cd in fresh diet: Cd I: 0.73, Cd II: 3.70, Cd III: 6.85, Cd IV: 41.71 and Cd V: 77.53 mg kg(-1)) and a control group (C) were set up. The results of the experiment showed that exposure to higher concentrations of Cd (41.71 and 77.53 mg kg(-1)) had a significant influence on development and redox status of O. nubilalis larvae: (1) the development rate was strongly reduced resulting in a prolonged pupation time; (2) the survival rate of larvae was prominently lower; (3) bioaccumulation factor (measured in pupae) was reduced which indicated that larvae could accumulate Cd to a certain level; (4) the level of the lipid peroxidation was significantly higher, which points to oxidative damage; (5) the expression of Mtn was significantly up-regulated while Cat and GPx genes down-regulated. In conclusion, long term exposure to dietary Cd in a concentration of 41.7 mg kg(-1) and higher, induced oxidative stress and slowed down growth and development of O. nubilalis larvae. PB - Oxford : Pergamon-Elsevier Science Ltd. T2 - Chemosphere T1 - The effect of long term exposure to cadmium on Ostrinia nubilalis growth, development, survival rate and oxidative status SP - 125375 VL - 243 DO - 10.1016/j.chemosphere.2019.125375 ER -
@article{ author = "Vukašinović, Elvira L. and Celić, Tatjana and Kojić, Danijela and Franeta, Filip and Milić, Stanko and Ninkov, Jordana and Blagojević, Dusko and Purać, Jelena", year = "2020", abstract = "In this study the effect of long term exposure to cadmium (Cd) on Ostrinia nubilalis larval growth, development, survival rate and oxidative status was analyzed. Newly hatched first instar - L1 larvae were reared on a Cd contaminated diet until the larvae reached the final, fifth instar - L5 or developed into pupae. In total, six experimental groups, five treatments (concentrations of Cd in fresh diet: Cd I: 0.73, Cd II: 3.70, Cd III: 6.85, Cd IV: 41.71 and Cd V: 77.53 mg kg(-1)) and a control group (C) were set up. The results of the experiment showed that exposure to higher concentrations of Cd (41.71 and 77.53 mg kg(-1)) had a significant influence on development and redox status of O. nubilalis larvae: (1) the development rate was strongly reduced resulting in a prolonged pupation time; (2) the survival rate of larvae was prominently lower; (3) bioaccumulation factor (measured in pupae) was reduced which indicated that larvae could accumulate Cd to a certain level; (4) the level of the lipid peroxidation was significantly higher, which points to oxidative damage; (5) the expression of Mtn was significantly up-regulated while Cat and GPx genes down-regulated. In conclusion, long term exposure to dietary Cd in a concentration of 41.7 mg kg(-1) and higher, induced oxidative stress and slowed down growth and development of O. nubilalis larvae.", publisher = "Oxford : Pergamon-Elsevier Science Ltd.", journal = "Chemosphere", title = "The effect of long term exposure to cadmium on Ostrinia nubilalis growth, development, survival rate and oxidative status", pages = "125375", volume = "243", doi = "10.1016/j.chemosphere.2019.125375" }
Vukašinović, E. L., Celić, T., Kojić, D., Franeta, F., Milić, S., Ninkov, J., Blagojević, D.,& Purać, J.. (2020). The effect of long term exposure to cadmium on Ostrinia nubilalis growth, development, survival rate and oxidative status. in Chemosphere Oxford : Pergamon-Elsevier Science Ltd.., 243, 125375. https://doi.org/10.1016/j.chemosphere.2019.125375
Vukašinović EL, Celić T, Kojić D, Franeta F, Milić S, Ninkov J, Blagojević D, Purać J. The effect of long term exposure to cadmium on Ostrinia nubilalis growth, development, survival rate and oxidative status. in Chemosphere. 2020;243:125375. doi:10.1016/j.chemosphere.2019.125375 .
Vukašinović, Elvira L., Celić, Tatjana, Kojić, Danijela, Franeta, Filip, Milić, Stanko, Ninkov, Jordana, Blagojević, Dusko, Purać, Jelena, "The effect of long term exposure to cadmium on Ostrinia nubilalis growth, development, survival rate and oxidative status" in Chemosphere, 243 (2020):125375, https://doi.org/10.1016/j.chemosphere.2019.125375 . .