Cost-effective microfluidic electronic devices for optimal drug administration based on fractional pharmacokinetics for leukemia treatments

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Cost-effective microfluidic electronic devices for optimal drug administration based on fractional pharmacokinetics for leukemia treatments (en)
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Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content

Tepavčević, Vesna; Cvejić, Jelena; Posa, Mihalj; Bjelica, Artur; Miladinović, Jegor; Rizou, Myrto; Aldawoud, Turki M. S.; Galanakis, Charis M.

(Academic Press Inc Elsevier Science, San Diego, 2021)

TY  - JOUR
AU  - Tepavčević, Vesna
AU  - Cvejić, Jelena
AU  - Posa, Mihalj
AU  - Bjelica, Artur
AU  - Miladinović, Jegor
AU  - Rizou, Myrto
AU  - Aldawoud, Turki M. S.
AU  - Galanakis, Charis M.
PY  - 2021
UR  - http://fiver.ifvcns.rs/handle/123456789/2094
AB  - Isoflavones are phytoestrogens with various types of biological activity. Soybean (Glycine max (L.) Merr.) is the most abundant source of isoflavones in human nutrition. The present study aims to classify the different soybean genotypes according to their isoflavone contents. HPLC analysis of isoflavone content in 22 soybean genotypes was performed. The average content of individual isoflavones in the genotypes analyzed ranged from 2.8 mu g/g to 1069,9 mu g/g while the most abundant component among the 22 genotypes was malonyl-genistin. The majority of isoflavones had a significantly higher concentration (p  lt  0.05) in the hybrid genotypes compared to parental genotypes implying heterosis. The principal component analysis (PCA) on isoflavone content and composition, including results in 83 genotypes, was conducted. The contents of daidzein and genistein were positively correlated, which could be explained by their biosynthetic pathways. Using the PCA, analyzed genotypes divided into six coherent groups regarding their specific isoflavone content. Malonyl-genistin and malonyl-daidzin were the most abundant components. Moreover, the significance of the cultivation year on the isoflavone content in soybean was pointed out. The overall results suggested the possibility of selection of suitable soybean extracts according to the content of malonyl-genistin.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Journal of Food Composition & Analysis
T1  - Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content
VL  - 95
DO  - 10.1016/j.jfca.2020.103670
ER  - 
@article{
author = "Tepavčević, Vesna and Cvejić, Jelena and Posa, Mihalj and Bjelica, Artur and Miladinović, Jegor and Rizou, Myrto and Aldawoud, Turki M. S. and Galanakis, Charis M.",
year = "2021",
abstract = "Isoflavones are phytoestrogens with various types of biological activity. Soybean (Glycine max (L.) Merr.) is the most abundant source of isoflavones in human nutrition. The present study aims to classify the different soybean genotypes according to their isoflavone contents. HPLC analysis of isoflavone content in 22 soybean genotypes was performed. The average content of individual isoflavones in the genotypes analyzed ranged from 2.8 mu g/g to 1069,9 mu g/g while the most abundant component among the 22 genotypes was malonyl-genistin. The majority of isoflavones had a significantly higher concentration (p  lt  0.05) in the hybrid genotypes compared to parental genotypes implying heterosis. The principal component analysis (PCA) on isoflavone content and composition, including results in 83 genotypes, was conducted. The contents of daidzein and genistein were positively correlated, which could be explained by their biosynthetic pathways. Using the PCA, analyzed genotypes divided into six coherent groups regarding their specific isoflavone content. Malonyl-genistin and malonyl-daidzin were the most abundant components. Moreover, the significance of the cultivation year on the isoflavone content in soybean was pointed out. The overall results suggested the possibility of selection of suitable soybean extracts according to the content of malonyl-genistin.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Journal of Food Composition & Analysis",
title = "Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content",
volume = "95",
doi = "10.1016/j.jfca.2020.103670"
}
Tepavčević, V., Cvejić, J., Posa, M., Bjelica, A., Miladinović, J., Rizou, M., Aldawoud, T. M. S.,& Galanakis, C. M.. (2021). Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content. in Journal of Food Composition & Analysis
Academic Press Inc Elsevier Science, San Diego., 95.
https://doi.org/10.1016/j.jfca.2020.103670
Tepavčević V, Cvejić J, Posa M, Bjelica A, Miladinović J, Rizou M, Aldawoud TMS, Galanakis CM. Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content. in Journal of Food Composition & Analysis. 2021;95.
doi:10.1016/j.jfca.2020.103670 .
Tepavčević, Vesna, Cvejić, Jelena, Posa, Mihalj, Bjelica, Artur, Miladinović, Jegor, Rizou, Myrto, Aldawoud, Turki M. S., Galanakis, Charis M., "Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content" in Journal of Food Composition & Analysis, 95 (2021),
https://doi.org/10.1016/j.jfca.2020.103670 . .
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Isoflavone Composition, Total Phenolic Content and Antioxidant Capacity of Soybeans with Colored Seed Coat

Bursać, Mira; Atanacković-Krstonosić, Milica; Miladinović, Jegor; Malenčić, Ðorđe; Gvozdenović, Ljiljana; Cvejić, Jelena

(Natural Product Incorporation, 2017)

TY  - JOUR
AU  - Bursać, Mira
AU  - Atanacković-Krstonosić, Milica
AU  - Miladinović, Jegor
AU  - Malenčić, Ðorđe
AU  - Gvozdenović, Ljiljana
AU  - Cvejić, Jelena
PY  - 2017
UR  - http://fiver.ifvcns.rs/handle/123456789/1715
AB  - The influence of soybean seed coat color and genotype on antioxidant capacity, phenolic content and isoflavone profile was investigated. Isoflavone content and composition of 21 seed samples - yellow, green, brown, black and rarely mentioned ocher and reddish, were determined by high-performance liquid chromatographic analysis. Antioxidant capacity and total phenolic content (TPC) were evaluated spectrophotometrically. Significant correlation between total isoflavone content and total genisteins was established in all colored groups. Total isoflavone content was in the range from 2.11 mg/g in a green wrinkled sample to 5.24 mg/g in yellow seed. It was found that black genotypes had the highest TPC and antioxidant capacity, which were significantly different (p lt 0.05) from other colored soybeans. The obtained interconnections among analyzed isoflavones can be used as a model for estimation of their specific content.
PB  - Natural Product Incorporation
T2  - Natural Product Communications
T1  - Isoflavone Composition, Total Phenolic Content and Antioxidant Capacity of Soybeans with Colored Seed Coat
EP  - 532
IS  - 4
SP  - 527
VL  - 12
DO  - 10.1177/1934578x1701200417
ER  - 
@article{
author = "Bursać, Mira and Atanacković-Krstonosić, Milica and Miladinović, Jegor and Malenčić, Ðorđe and Gvozdenović, Ljiljana and Cvejić, Jelena",
year = "2017",
abstract = "The influence of soybean seed coat color and genotype on antioxidant capacity, phenolic content and isoflavone profile was investigated. Isoflavone content and composition of 21 seed samples - yellow, green, brown, black and rarely mentioned ocher and reddish, were determined by high-performance liquid chromatographic analysis. Antioxidant capacity and total phenolic content (TPC) were evaluated spectrophotometrically. Significant correlation between total isoflavone content and total genisteins was established in all colored groups. Total isoflavone content was in the range from 2.11 mg/g in a green wrinkled sample to 5.24 mg/g in yellow seed. It was found that black genotypes had the highest TPC and antioxidant capacity, which were significantly different (p lt 0.05) from other colored soybeans. The obtained interconnections among analyzed isoflavones can be used as a model for estimation of their specific content.",
publisher = "Natural Product Incorporation",
journal = "Natural Product Communications",
title = "Isoflavone Composition, Total Phenolic Content and Antioxidant Capacity of Soybeans with Colored Seed Coat",
pages = "532-527",
number = "4",
volume = "12",
doi = "10.1177/1934578x1701200417"
}
Bursać, M., Atanacković-Krstonosić, M., Miladinović, J., Malenčić, Ð., Gvozdenović, L.,& Cvejić, J.. (2017). Isoflavone Composition, Total Phenolic Content and Antioxidant Capacity of Soybeans with Colored Seed Coat. in Natural Product Communications
Natural Product Incorporation., 12(4), 527-532.
https://doi.org/10.1177/1934578x1701200417
Bursać M, Atanacković-Krstonosić M, Miladinović J, Malenčić Ð, Gvozdenović L, Cvejić J. Isoflavone Composition, Total Phenolic Content and Antioxidant Capacity of Soybeans with Colored Seed Coat. in Natural Product Communications. 2017;12(4):527-532.
doi:10.1177/1934578x1701200417 .
Bursać, Mira, Atanacković-Krstonosić, Milica, Miladinović, Jegor, Malenčić, Ðorđe, Gvozdenović, Ljiljana, Cvejić, Jelena, "Isoflavone Composition, Total Phenolic Content and Antioxidant Capacity of Soybeans with Colored Seed Coat" in Natural Product Communications, 12, no. 4 (2017):527-532,
https://doi.org/10.1177/1934578x1701200417 . .
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