TY  - CONF
AU  - Popov, Olivera
AU  - Leovac, Strahinja
AU  - Despotovski, Teodora
AU  - Karaman, Maja
AU  - Gadžurić, Slobodan
AU  - Pogorelc, Eva
AU  - Čapelja, Eleonora
PY  - 2022
UR  - http://fiver.ifvcns.rs/handle/123456789/3213
AB  - Traditionally, mold control usually involves usage of highly toxic compounds, and this practice must be replaced with more environmentally friendly solutions (green chemistry). In this paper, antifungal activity of five newly synthesized ionic liquids (IL) was tested, in vitro. All ionic liquids are based on N-decyl- N, N, N-trimethylammonium chloride which differs only by a single substituent on a quaternary N- atom. The antifungal activity of IL was tested on Fusarium, Aspergillus, Alternaria, Trichoderma and Penicillium strains using the microdilution method by determining the minimal inhibitory and minimal fungicidal concentrations. Selected genera are major problem in food industry since they are the primary pathogens of agronomically important plants, as well as mycotoxin producers. All five IL used in this study showed antifungal effect in the range of 0.002 mol/dm3 to 0.036 mol/dm3. The greatest antifungal activity was observed when strains were treated with (C2OH)C10DMACI and (C2OOEt)C10DMACI IL. Results obtained in this study showed that all examined ILs have the potential to be used as effective antifungal agents.
PB  - Novi Sad : Matica srpska
C3  - Knjiga rezimea, 7. međunarodni naučni skup "Mikologija, mikotoksikologija i mikoze", Novi Sad, 2-3. jun 2022.
T1  - Antifungal activity of surfactant ionic liquids on mycotoxigenic molds
EP  - 34
SP  - 34
UR  - https://hdl.handle.net/21.15107/rcub_fiver_3213
ER  - 

@conference{
author = "Popov, Olivera and Leovac, Strahinja and Despotovski, Teodora and Karaman, Maja and Gadžurić, Slobodan and Pogorelc, Eva and Čapelja, Eleonora",
year = "2022",
abstract = "Traditionally, mold control usually involves usage of highly toxic compounds, and this practice must be replaced with more environmentally friendly solutions (green chemistry). In this paper, antifungal activity of five newly synthesized ionic liquids (IL) was tested, in vitro. All ionic liquids are based on N-decyl- N, N, N-trimethylammonium chloride which differs only by a single substituent on a quaternary N- atom. The antifungal activity of IL was tested on Fusarium, Aspergillus, Alternaria, Trichoderma and Penicillium strains using the microdilution method by determining the minimal inhibitory and minimal fungicidal concentrations. Selected genera are major problem in food industry since they are the primary pathogens of agronomically important plants, as well as mycotoxin producers. All five IL used in this study showed antifungal effect in the range of 0.002 mol/dm3 to 0.036 mol/dm3. The greatest antifungal activity was observed when strains were treated with (C2OH)C10DMACI and (C2OOEt)C10DMACI IL. Results obtained in this study showed that all examined ILs have the potential to be used as effective antifungal agents.",
publisher = "Novi Sad : Matica srpska",
journal = "Knjiga rezimea, 7. međunarodni naučni skup "Mikologija, mikotoksikologija i mikoze", Novi Sad, 2-3. jun 2022.",
title = "Antifungal activity of surfactant ionic liquids on mycotoxigenic molds",
pages = "34-34",
url = "https://hdl.handle.net/21.15107/rcub_fiver_3213"
}

Popov, O., Leovac, S., Despotovski, T., Karaman, M., Gadžurić, S., Pogorelc, E.,& Čapelja, E.. (2022). Antifungal activity of surfactant ionic liquids on mycotoxigenic molds. in Knjiga rezimea, 7. međunarodni naučni skup "Mikologija, mikotoksikologija i mikoze", Novi Sad, 2-3. jun 2022.
Novi Sad : Matica srpska., 34-34.
https://hdl.handle.net/21.15107/rcub_fiver_3213

Popov O, Leovac S, Despotovski T, Karaman M, Gadžurić S, Pogorelc E, Čapelja E. Antifungal activity of surfactant ionic liquids on mycotoxigenic molds. in Knjiga rezimea, 7. međunarodni naučni skup "Mikologija, mikotoksikologija i mikoze", Novi Sad, 2-3. jun 2022.. 2022;:34-34.
https://hdl.handle.net/21.15107/rcub_fiver_3213 .

Popov, Olivera, Leovac, Strahinja, Despotovski, Teodora, Karaman, Maja, Gadžurić, Slobodan, Pogorelc, Eva, Čapelja, Eleonora, "Antifungal activity of surfactant ionic liquids on mycotoxigenic molds" in Knjiga rezimea, 7. međunarodni naučni skup "Mikologija, mikotoksikologija i mikoze", Novi Sad, 2-3. jun 2022. (2022):34-34,
https://hdl.handle.net/21.15107/rcub_fiver_3213 .

TY  - JOUR
AU  - Karaman, Maja
AU  - Vranes, Milan
AU  - Tot, Aleksandar
AU  - Papović, Snezana
AU  - Miljaković, Dragana
AU  - Gadžurić, Slobodan
AU  - Ignjatov, Maja
PY  - 2020
UR  - http://fiver.ifvcns.rs/handle/123456789/1968
AB  - The fungal genus Alternaria Nees 1816 includes the most prevalent pathogenic species that can cause crop diseases such as blight, black spot, and dark leaf spot. In accordance with the aim of developing modern sustainable approaches in agriculture for the replacement of synthetic and toxic substances with environmentally friendly alternatives, the objective of this study was to examine thein vitro antifungal activities of 18 newly synthesized ionic liquids (ILs) against three Alternaria strains: A. padwickii, A. dauci and A. linicola. The antifungal activities of the ILs were estimated via a microdilution method to establish minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values. The results confirmed that 17 of the 18 ILs showed strain specificity, including good antifungal activity toward Alternaria strains, with MIC and MFC values in the range of 0.04 to 0.43 mol dm(-3). The strongest antifungal effects toward all analyzed Alternaria strains were displayed by the compounds with long alkyl chains: [omim][Cl] (MIC/MFC: 0.042 mol dm(-3)), [dmim][Cl] (MIC/MFC: 0.043 mol dm(-3)), [ddmim][Cl] (MIC/MFC: 0.053 mol dm(-3)), [ddTSC][Br] (MIC/MFC: 0.053 mol dm(-3)), and [Allyl-mim][Cl] (MIC/MFC: 0.054 mol dm(-3)). The introduction of oxygen as a hydroxyl group resulted in less-pronounced toxicity towards Alternaria compared to the introduction of an ether group, while the contribution of the hydroxyl group was shown to be a more determining factor than the prolongation of the side-chain, resulting in overall fungicidal activity decrease. Our results indicate the possibility that the most effective ILs ([Allyl-mim][Cl], [omim][Cl], [dmim][Cl], [ddmim][Cl], [bTSC][Br], [hTSC][Br], [oTSC][Br], [dTSC][Br], and [ddTSC][Br]) could be applied to the control of plant diseases caused by Alternaria species, based on their potential as an environmentally friendly crop protection approach. Since salts based on TSC cations are significantly cheaper to synthesize, stable under mild conditions, and environmentally friendly after degradation, thiosemicarbazidium-based ILs can be a suitable replacement for commercially available imidazolium ILs.
PB  - Royal Soc Chemistry, Cambridge
T2  - RSC Advances
T1  - Ionic liquids as potentially new antifungal agents against Alternaria species
EP  - 22323
IS  - 38
SP  - 22318
VL  - 10
DO  - 10.1039/d0ra02475a
ER  - 

@article{
author = "Karaman, Maja and Vranes, Milan and Tot, Aleksandar and Papović, Snezana and Miljaković, Dragana and Gadžurić, Slobodan and Ignjatov, Maja",
year = "2020",
abstract = "The fungal genus Alternaria Nees 1816 includes the most prevalent pathogenic species that can cause crop diseases such as blight, black spot, and dark leaf spot. In accordance with the aim of developing modern sustainable approaches in agriculture for the replacement of synthetic and toxic substances with environmentally friendly alternatives, the objective of this study was to examine thein vitro antifungal activities of 18 newly synthesized ionic liquids (ILs) against three Alternaria strains: A. padwickii, A. dauci and A. linicola. The antifungal activities of the ILs were estimated via a microdilution method to establish minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values. The results confirmed that 17 of the 18 ILs showed strain specificity, including good antifungal activity toward Alternaria strains, with MIC and MFC values in the range of 0.04 to 0.43 mol dm(-3). The strongest antifungal effects toward all analyzed Alternaria strains were displayed by the compounds with long alkyl chains: [omim][Cl] (MIC/MFC: 0.042 mol dm(-3)), [dmim][Cl] (MIC/MFC: 0.043 mol dm(-3)), [ddmim][Cl] (MIC/MFC: 0.053 mol dm(-3)), [ddTSC][Br] (MIC/MFC: 0.053 mol dm(-3)), and [Allyl-mim][Cl] (MIC/MFC: 0.054 mol dm(-3)). The introduction of oxygen as a hydroxyl group resulted in less-pronounced toxicity towards Alternaria compared to the introduction of an ether group, while the contribution of the hydroxyl group was shown to be a more determining factor than the prolongation of the side-chain, resulting in overall fungicidal activity decrease. Our results indicate the possibility that the most effective ILs ([Allyl-mim][Cl], [omim][Cl], [dmim][Cl], [ddmim][Cl], [bTSC][Br], [hTSC][Br], [oTSC][Br], [dTSC][Br], and [ddTSC][Br]) could be applied to the control of plant diseases caused by Alternaria species, based on their potential as an environmentally friendly crop protection approach. Since salts based on TSC cations are significantly cheaper to synthesize, stable under mild conditions, and environmentally friendly after degradation, thiosemicarbazidium-based ILs can be a suitable replacement for commercially available imidazolium ILs.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "RSC Advances",
title = "Ionic liquids as potentially new antifungal agents against Alternaria species",
pages = "22323-22318",
number = "38",
volume = "10",
doi = "10.1039/d0ra02475a"
}

Karaman, M., Vranes, M., Tot, A., Papović, S., Miljaković, D., Gadžurić, S.,& Ignjatov, M.. (2020). Ionic liquids as potentially new antifungal agents against Alternaria species. in RSC Advances
Royal Soc Chemistry, Cambridge., 10(38), 22318-22323.
https://doi.org/10.1039/d0ra02475a

Karaman M, Vranes M, Tot A, Papović S, Miljaković D, Gadžurić S, Ignjatov M. Ionic liquids as potentially new antifungal agents against Alternaria species. in RSC Advances. 2020;10(38):22318-22323.
doi:10.1039/d0ra02475a .

Karaman, Maja, Vranes, Milan, Tot, Aleksandar, Papović, Snezana, Miljaković, Dragana, Gadžurić, Slobodan, Ignjatov, Maja, "Ionic liquids as potentially new antifungal agents against Alternaria species" in RSC Advances, 10, no. 38 (2020):22318-22323,
https://doi.org/10.1039/d0ra02475a . .

TY  - JOUR
AU  - Spremo, Nemanja
AU  - Bešir, Nataša
AU  - Vraneš, Milan
AU  - Gadžurić, Slobodan
AU  - Ignjatov, Maja
AU  - Bjelić, Dragana
AU  - Karaman, Maja
PY  - 2018
UR  - http://fiver.ifvcns.rs/handle/123456789/2534
AB  - A modern sustainable approach in agricultural practice would
be a replacement of synthetic and toxic substances in the
treatment of crop with benign and environmentally friendly
compounds, by using principles of green chemistry. One of
the possible directions could be using of ionic liquids (ILs),
salts with melting points below 100 °C, which are well-known
for manifesting antimicrobial activity. ILs can be used in the
development of novel sources of antimicrobial agents such as
antiseptics, biocides and antifungal agents. Furthermore, ILs
have already been reported as alternative ‘green’ solvents for a
wide range of reactions and technological processes. Considering the importance of research in the area of bioactivity of
ILs for discovery of new green ILs for diff erent purposes, the
aim of this study was to examine antifungal activity of nine
newly synthesized ILs against phytopathogenic Alternaria
strains isolated from from rice (A. padwickii), carrot (A. dauci) and linseed (A. linicola). Antifungal eff ect was estimated
by micro-plate microdilution method for establishing minimum inhibitory (MIC) and minimum fungicidal concentration (MFC). All ionic liquids showed strain specifi c but good
antifungal activity on Alternaria strains with MIC and MFC
detected at the range from 9.23 mg/ml to 75.89 mg/ml. Only
in case of the 1-(4-hydroxy-2-oxy)butyl -3-methylimidazolium chloride [OHC2OC2mIm][Cl], no antifungal eff ect on
A. dauci were observed. Comparing to A. padwickii and A.
dauci., A. linicola showed higher sensitivity to all tested ILs.
Th e obtained results indicate the possibility of usage of ILs
in biocontrol of plant diseases, representing their application
in crop protection. However, further research is necessary in
order to examine their toxicity and biodegradability in the environment.
PB  - Belgrade : University of Belgrade, Institute of Botany and Botanical Garden Jevremovac
T2  - Botanica Serbica, supplement 1 (Book of Abstracts, 7th Balkan Botanical Congress, 10-14 September 2018, Novi Sad, Serbia)
T1  - Antifungal activities of ionic liquids against phytopathogenic Alternaria spp. strains
EP  - 169
IS  - 42
SP  - 169
UR  - https://hdl.handle.net/21.15107/rcub_fiver_2534
ER  - 

@article{
author = "Spremo, Nemanja and Bešir, Nataša and Vraneš, Milan and Gadžurić, Slobodan and Ignjatov, Maja and Bjelić, Dragana and Karaman, Maja",
year = "2018",
abstract = "A modern sustainable approach in agricultural practice would
be a replacement of synthetic and toxic substances in the
treatment of crop with benign and environmentally friendly
compounds, by using principles of green chemistry. One of
the possible directions could be using of ionic liquids (ILs),
salts with melting points below 100 °C, which are well-known
for manifesting antimicrobial activity. ILs can be used in the
development of novel sources of antimicrobial agents such as
antiseptics, biocides and antifungal agents. Furthermore, ILs
have already been reported as alternative ‘green’ solvents for a
wide range of reactions and technological processes. Considering the importance of research in the area of bioactivity of
ILs for discovery of new green ILs for diff erent purposes, the
aim of this study was to examine antifungal activity of nine
newly synthesized ILs against phytopathogenic Alternaria
strains isolated from from rice (A. padwickii), carrot (A. dauci) and linseed (A. linicola). Antifungal eff ect was estimated
by micro-plate microdilution method for establishing minimum inhibitory (MIC) and minimum fungicidal concentration (MFC). All ionic liquids showed strain specifi c but good
antifungal activity on Alternaria strains with MIC and MFC
detected at the range from 9.23 mg/ml to 75.89 mg/ml. Only
in case of the 1-(4-hydroxy-2-oxy)butyl -3-methylimidazolium chloride [OHC2OC2mIm][Cl], no antifungal eff ect on
A. dauci were observed. Comparing to A. padwickii and A.
dauci., A. linicola showed higher sensitivity to all tested ILs.
Th e obtained results indicate the possibility of usage of ILs
in biocontrol of plant diseases, representing their application
in crop protection. However, further research is necessary in
order to examine their toxicity and biodegradability in the environment.",
publisher = "Belgrade : University of Belgrade, Institute of Botany and Botanical Garden Jevremovac",
journal = "Botanica Serbica, supplement 1 (Book of Abstracts, 7th Balkan Botanical Congress, 10-14 September 2018, Novi Sad, Serbia)",
title = "Antifungal activities of ionic liquids against phytopathogenic Alternaria spp. strains",
pages = "169-169",
number = "42",
url = "https://hdl.handle.net/21.15107/rcub_fiver_2534"
}

Spremo, N., Bešir, N., Vraneš, M., Gadžurić, S., Ignjatov, M., Bjelić, D.,& Karaman, M.. (2018). Antifungal activities of ionic liquids against phytopathogenic Alternaria spp. strains. in Botanica Serbica, supplement 1 (Book of Abstracts, 7th Balkan Botanical Congress, 10-14 September 2018, Novi Sad, Serbia)
Belgrade : University of Belgrade, Institute of Botany and Botanical Garden Jevremovac.(42), 169-169.
https://hdl.handle.net/21.15107/rcub_fiver_2534

Spremo N, Bešir N, Vraneš M, Gadžurić S, Ignjatov M, Bjelić D, Karaman M. Antifungal activities of ionic liquids against phytopathogenic Alternaria spp. strains. in Botanica Serbica, supplement 1 (Book of Abstracts, 7th Balkan Botanical Congress, 10-14 September 2018, Novi Sad, Serbia). 2018;(42):169-169.
https://hdl.handle.net/21.15107/rcub_fiver_2534 .

Spremo, Nemanja, Bešir, Nataša, Vraneš, Milan, Gadžurić, Slobodan, Ignjatov, Maja, Bjelić, Dragana, Karaman, Maja, "Antifungal activities of ionic liquids against phytopathogenic Alternaria spp. strains" in Botanica Serbica, supplement 1 (Book of Abstracts, 7th Balkan Botanical Congress, 10-14 September 2018, Novi Sad, Serbia), no. 42 (2018):169-169,
https://hdl.handle.net/21.15107/rcub_fiver_2534 .