TY  - JOUR
AU  - Tepavčević, Vesna
AU  - Cvejić, Jelena
AU  - Posa, Mihalj
AU  - Bjelica, Artur
AU  - Miladinović, Jegor
AU  - Rizou, Myrto
AU  - Aldawoud, Turki M. S.
AU  - Galanakis, Charis M.
PY  - 2021
UR  - http://fiver.ifvcns.rs/handle/123456789/2094
AB  - Isoflavones are phytoestrogens with various types of biological activity. Soybean (Glycine max (L.) Merr.) is the most abundant source of isoflavones in human nutrition. The present study aims to classify the different soybean genotypes according to their isoflavone contents. HPLC analysis of isoflavone content in 22 soybean genotypes was performed. The average content of individual isoflavones in the genotypes analyzed ranged from 2.8 mu g/g to 1069,9 mu g/g while the most abundant component among the 22 genotypes was malonyl-genistin. The majority of isoflavones had a significantly higher concentration (p  lt  0.05) in the hybrid genotypes compared to parental genotypes implying heterosis. The principal component analysis (PCA) on isoflavone content and composition, including results in 83 genotypes, was conducted. The contents of daidzein and genistein were positively correlated, which could be explained by their biosynthetic pathways. Using the PCA, analyzed genotypes divided into six coherent groups regarding their specific isoflavone content. Malonyl-genistin and malonyl-daidzin were the most abundant components. Moreover, the significance of the cultivation year on the isoflavone content in soybean was pointed out. The overall results suggested the possibility of selection of suitable soybean extracts according to the content of malonyl-genistin.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Journal of Food Composition & Analysis
T1  - Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content
VL  - 95
DO  - 10.1016/j.jfca.2020.103670
ER  - 

@article{
author = "Tepavčević, Vesna and Cvejić, Jelena and Posa, Mihalj and Bjelica, Artur and Miladinović, Jegor and Rizou, Myrto and Aldawoud, Turki M. S. and Galanakis, Charis M.",
year = "2021",
abstract = "Isoflavones are phytoestrogens with various types of biological activity. Soybean (Glycine max (L.) Merr.) is the most abundant source of isoflavones in human nutrition. The present study aims to classify the different soybean genotypes according to their isoflavone contents. HPLC analysis of isoflavone content in 22 soybean genotypes was performed. The average content of individual isoflavones in the genotypes analyzed ranged from 2.8 mu g/g to 1069,9 mu g/g while the most abundant component among the 22 genotypes was malonyl-genistin. The majority of isoflavones had a significantly higher concentration (p  lt  0.05) in the hybrid genotypes compared to parental genotypes implying heterosis. The principal component analysis (PCA) on isoflavone content and composition, including results in 83 genotypes, was conducted. The contents of daidzein and genistein were positively correlated, which could be explained by their biosynthetic pathways. Using the PCA, analyzed genotypes divided into six coherent groups regarding their specific isoflavone content. Malonyl-genistin and malonyl-daidzin were the most abundant components. Moreover, the significance of the cultivation year on the isoflavone content in soybean was pointed out. The overall results suggested the possibility of selection of suitable soybean extracts according to the content of malonyl-genistin.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Journal of Food Composition & Analysis",
title = "Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content",
volume = "95",
doi = "10.1016/j.jfca.2020.103670"
}

Tepavčević, V., Cvejić, J., Posa, M., Bjelica, A., Miladinović, J., Rizou, M., Aldawoud, T. M. S.,& Galanakis, C. M.. (2021). Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content. in Journal of Food Composition & Analysis
Academic Press Inc Elsevier Science, San Diego., 95.
https://doi.org/10.1016/j.jfca.2020.103670

Tepavčević V, Cvejić J, Posa M, Bjelica A, Miladinović J, Rizou M, Aldawoud TMS, Galanakis CM. Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content. in Journal of Food Composition & Analysis. 2021;95.
doi:10.1016/j.jfca.2020.103670 .

Tepavčević, Vesna, Cvejić, Jelena, Posa, Mihalj, Bjelica, Artur, Miladinović, Jegor, Rizou, Myrto, Aldawoud, Turki M. S., Galanakis, Charis M., "Classification and discrimination of soybean (Glycine max (L.) Merr.) genotypes based on their isoflavone content" in Journal of Food Composition & Analysis, 95 (2021),
https://doi.org/10.1016/j.jfca.2020.103670 . .

TY  - JOUR
AU  - Cvejić, Jelena
AU  - Malenčić, Ðorđe
AU  - Tepavčević, Vesna
AU  - Posa, Mihalj
AU  - Miladinović, Jegor
PY  - 2009
UR  - http://fiver.ifvcns.rs/handle/123456789/772
AB  - The growing clinical interest and use of soybean-based food products and extracts to increase dietary phytoestrogen intake have led to medical interest in the precise determination of the phytoestrogen composition of soybean products. We have analyzed the composition of these compounds in 20 domestic and introduced varieties of genetically non-modified soybean genotypes grown under the same agroecological conditions. The isoflavone content of soybeans cultivated in this region of Serbia has not been previously reported. The assays were performed, after extraction with methanol-water (8:2, v/v), by C-18 reversed phase high-performance liquid chromatography coupled with photodiode array detection. The total phytoestrogen concentration was found to be between 2.24 and 3.79 mg g(-1) dry bean weight. The total concentration of daidzein and its derivatives ranged from 0.96 to 1.82 mg g(-1), total glyciteines from 0.34-0.53 mg g(-1), and all genistein derivatives from 0.86-1.67 mg g(-1) dry bean weight. Given the high biological potency of phytoestrogens and their metabolic conversion products, our data suggest that phytoestrogen content screening could be a useful tool in the selection of soybean genotypes with improved health promoting characteristics.
PB  - Natural Product Incorporation
T2  - Natural Product Communications
T1  - Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia
EP  - 1074
IS  - 8
SP  - 1069
VL  - 4
DO  - 10.1177/1934578x0900400810
ER  - 

@article{
author = "Cvejić, Jelena and Malenčić, Ðorđe and Tepavčević, Vesna and Posa, Mihalj and Miladinović, Jegor",
year = "2009",
abstract = "The growing clinical interest and use of soybean-based food products and extracts to increase dietary phytoestrogen intake have led to medical interest in the precise determination of the phytoestrogen composition of soybean products. We have analyzed the composition of these compounds in 20 domestic and introduced varieties of genetically non-modified soybean genotypes grown under the same agroecological conditions. The isoflavone content of soybeans cultivated in this region of Serbia has not been previously reported. The assays were performed, after extraction with methanol-water (8:2, v/v), by C-18 reversed phase high-performance liquid chromatography coupled with photodiode array detection. The total phytoestrogen concentration was found to be between 2.24 and 3.79 mg g(-1) dry bean weight. The total concentration of daidzein and its derivatives ranged from 0.96 to 1.82 mg g(-1), total glyciteines from 0.34-0.53 mg g(-1), and all genistein derivatives from 0.86-1.67 mg g(-1) dry bean weight. Given the high biological potency of phytoestrogens and their metabolic conversion products, our data suggest that phytoestrogen content screening could be a useful tool in the selection of soybean genotypes with improved health promoting characteristics.",
publisher = "Natural Product Incorporation",
journal = "Natural Product Communications",
title = "Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia",
pages = "1074-1069",
number = "8",
volume = "4",
doi = "10.1177/1934578x0900400810"
}

Cvejić, J., Malenčić, Ð., Tepavčević, V., Posa, M.,& Miladinović, J.. (2009). Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia. in Natural Product Communications
Natural Product Incorporation., 4(8), 1069-1074.
https://doi.org/10.1177/1934578x0900400810

Cvejić J, Malenčić Ð, Tepavčević V, Posa M, Miladinović J. Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia. in Natural Product Communications. 2009;4(8):1069-1074.
doi:10.1177/1934578x0900400810 .

Cvejić, Jelena, Malenčić, Ðorđe, Tepavčević, Vesna, Posa, Mihalj, Miladinović, Jegor, "Determination of Phytoestrogen Composition in Soybean Cultivars in Serbia" in Natural Product Communications, 4, no. 8 (2009):1069-1074,
https://doi.org/10.1177/1934578x0900400810 . .