TY  - JOUR
AU  - Drinić, Zorica
AU  - Vladić, Jelena
AU  - Koren, Anamarija
AU  - Zeremski, Tijana
AU  - Stojanov, Nadežda
AU  - Tomić, Milan
AU  - Vidović, Senka
PY  - 2021
UR  - http://fiver.ifvcns.rs/handle/123456789/3435
AB  - In this work, different extraction techniques (soxhlet extraction, hydrodistillation, subcritical water extraction and supercritical carbon dioxide extraction followed by conventional extraction) were employed for the isolation of bioactive compounds from the areal parts of industrial hemp (Cannabis sativa L.). The extraction process parameters, time and temperature for subcritical water extraction and pressure, temperature and time for supercritical carbon dioxide extraction, on the extraction yield and the content of bioactive compounds from hemp were examined. As the plant material after supercritical carbon dioxide still contains hydrophilic compounds, conventional extraction was used for isolation of these. The content of cannabidiol, the main cannabinoid present in hemp, in supercritical carbon dioxide extracts was between 71.84–163.11 mg/g, while in soxhlet extract it was much lower (64.40 mg/g). In comparison to these the significantly lower cannabidiol content was detected in subcritical water extracts, ranging from 0.0039 to 0.0183 mg/mL. Comparing all applied extraction techniques, supercritical carbon dioxide followed by conventional extraction was selected as the most valuable process for bioactive compounds isolation for hemp.
PB  - Elsevier
T2  - Industrial Crops and Products
T1  - Application of conventional and high-pressure extraction techniques for the isolation of bioactive compounds from the aerial part of hemp (Cannabis sativa L.) assortment Helena
SP  - 113908
VL  - 171
DO  - 10.1016/j.indcrop.2021.113908
ER  - 

@article{
author = "Drinić, Zorica and Vladić, Jelena and Koren, Anamarija and Zeremski, Tijana and Stojanov, Nadežda and Tomić, Milan and Vidović, Senka",
year = "2021",
abstract = "In this work, different extraction techniques (soxhlet extraction, hydrodistillation, subcritical water extraction and supercritical carbon dioxide extraction followed by conventional extraction) were employed for the isolation of bioactive compounds from the areal parts of industrial hemp (Cannabis sativa L.). The extraction process parameters, time and temperature for subcritical water extraction and pressure, temperature and time for supercritical carbon dioxide extraction, on the extraction yield and the content of bioactive compounds from hemp were examined. As the plant material after supercritical carbon dioxide still contains hydrophilic compounds, conventional extraction was used for isolation of these. The content of cannabidiol, the main cannabinoid present in hemp, in supercritical carbon dioxide extracts was between 71.84–163.11 mg/g, while in soxhlet extract it was much lower (64.40 mg/g). In comparison to these the significantly lower cannabidiol content was detected in subcritical water extracts, ranging from 0.0039 to 0.0183 mg/mL. Comparing all applied extraction techniques, supercritical carbon dioxide followed by conventional extraction was selected as the most valuable process for bioactive compounds isolation for hemp.",
publisher = "Elsevier",
journal = "Industrial Crops and Products",
title = "Application of conventional and high-pressure extraction techniques for the isolation of bioactive compounds from the aerial part of hemp (Cannabis sativa L.) assortment Helena",
pages = "113908",
volume = "171",
doi = "10.1016/j.indcrop.2021.113908"
}

Drinić, Z., Vladić, J., Koren, A., Zeremski, T., Stojanov, N., Tomić, M.,& Vidović, S.. (2021). Application of conventional and high-pressure extraction techniques for the isolation of bioactive compounds from the aerial part of hemp (Cannabis sativa L.) assortment Helena. in Industrial Crops and Products
Elsevier., 171, 113908.
https://doi.org/10.1016/j.indcrop.2021.113908

Drinić Z, Vladić J, Koren A, Zeremski T, Stojanov N, Tomić M, Vidović S. Application of conventional and high-pressure extraction techniques for the isolation of bioactive compounds from the aerial part of hemp (Cannabis sativa L.) assortment Helena. in Industrial Crops and Products. 2021;171:113908.
doi:10.1016/j.indcrop.2021.113908 .

Drinić, Zorica, Vladić, Jelena, Koren, Anamarija, Zeremski, Tijana, Stojanov, Nadežda, Tomić, Milan, Vidović, Senka, "Application of conventional and high-pressure extraction techniques for the isolation of bioactive compounds from the aerial part of hemp (Cannabis sativa L.) assortment Helena" in Industrial Crops and Products, 171 (2021):113908,
https://doi.org/10.1016/j.indcrop.2021.113908 . .

TY  - JOUR
AU  - Drinić, Zorica
AU  - Vidović, Senka
AU  - Vladić, Jelena
AU  - Koren, Anamarija
AU  - Kiprovski, Biljana
AU  - Sikora, Vladimir
PY  - 2018
UR  - http://fiver.ifvcns.rs/handle/123456789/1789
AB  - In this study, water and various concentrations of ethanol in water (30 %, 50 %, 70 %, and 90 %) were used as a solvent in the extraction of two different samples of hemp (Cannabis sativa L.). The extraction yield, total phenols content, total flavonoids content, antioxidant activity, and reductive capacity were determined in the obtained extracts. The extraction yield was from 8.16 to 19.56 %, the content of total phenols was in the range from 5.85 to 17.05 mg GAE/g dw, and content of total flavonoids was in the range from 5.85 to 9.25 mg CE/g dw. Antioxidant activity was tested by DPPH assay and EC50 values were from 0.1331 to 0.7563 mg/mL, while EC50 values obtained by reducing power test ranged from 0.4450 to 1.1980 mg/mL. Ethanol/water mixture (50 %) was determined to be the best solvent for the extraction of phenolic compounds from both hemp samples. Total phenols content in 50 % ethanolic extracts were 17.05 mg/g dw and 9.25 mg/g dw for young and mature hemp, respectively.
PB  - Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd
T2  - Lekovite sirovine
T1  - Effect of extraction solvent on total polyphenols content and antioxidant activity of Cannabis sativa L.
EP  - 21
IS  - 38
SP  - 17
DO  - 10.5937/leksir1838017D
ER  - 

@article{
author = "Drinić, Zorica and Vidović, Senka and Vladić, Jelena and Koren, Anamarija and Kiprovski, Biljana and Sikora, Vladimir",
year = "2018",
abstract = "In this study, water and various concentrations of ethanol in water (30 %, 50 %, 70 %, and 90 %) were used as a solvent in the extraction of two different samples of hemp (Cannabis sativa L.). The extraction yield, total phenols content, total flavonoids content, antioxidant activity, and reductive capacity were determined in the obtained extracts. The extraction yield was from 8.16 to 19.56 %, the content of total phenols was in the range from 5.85 to 17.05 mg GAE/g dw, and content of total flavonoids was in the range from 5.85 to 9.25 mg CE/g dw. Antioxidant activity was tested by DPPH assay and EC50 values were from 0.1331 to 0.7563 mg/mL, while EC50 values obtained by reducing power test ranged from 0.4450 to 1.1980 mg/mL. Ethanol/water mixture (50 %) was determined to be the best solvent for the extraction of phenolic compounds from both hemp samples. Total phenols content in 50 % ethanolic extracts were 17.05 mg/g dw and 9.25 mg/g dw for young and mature hemp, respectively.",
publisher = "Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd",
journal = "Lekovite sirovine",
title = "Effect of extraction solvent on total polyphenols content and antioxidant activity of Cannabis sativa L.",
pages = "21-17",
number = "38",
doi = "10.5937/leksir1838017D"
}

Drinić, Z., Vidović, S., Vladić, J., Koren, A., Kiprovski, B.,& Sikora, V.. (2018). Effect of extraction solvent on total polyphenols content and antioxidant activity of Cannabis sativa L.. in Lekovite sirovine
Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd.(38), 17-21.
https://doi.org/10.5937/leksir1838017D

Drinić Z, Vidović S, Vladić J, Koren A, Kiprovski B, Sikora V. Effect of extraction solvent on total polyphenols content and antioxidant activity of Cannabis sativa L.. in Lekovite sirovine. 2018;(38):17-21.
doi:10.5937/leksir1838017D .

Drinić, Zorica, Vidović, Senka, Vladić, Jelena, Koren, Anamarija, Kiprovski, Biljana, Sikora, Vladimir, "Effect of extraction solvent on total polyphenols content and antioxidant activity of Cannabis sativa L." in Lekovite sirovine, no. 38 (2018):17-21,
https://doi.org/10.5937/leksir1838017D . .